Morgagni-Steawart-Morel syndrome: Case report

Abstract

Hyperostosis frontalis interna (HOFI) is characterized by the benign growth of the inner plate of the frontal bone. It is most common in older women. Etiology is unknown. Morgagni-Stewart-Morel syndrome (MSM) is characterized by HOFI, obesity, hirsutism and mental illnesses but these associations are mostly based only on case reports. MSM syndrome is a misunderstood and less reported pathology. The clinical presentation is not well defined and its finding is usually coincidental. The patient may present variable symptomatology. The idea that we should keep in mind is that HOFI represent the main pattern of MSM. Thus, it is highly important to specify the presence and degree of HOFI in radiological reports. ÖzHiperostozis frontalis interna(HOFI) frontal kemiğin iç tabulasının iyi huylu büyümesi ile karakterizedir. En sık yaşlı kadınlarda görülür. Etiyoloji bilinmemektedir. Morgagni-Stewart-Morel sendromu (MSM); HOFI, obezite, hirsutizm ve zihinsel rahatsızlıklar ile karakterizedir ancak bu ilişkiler çoğunlukla vaka raporlarına dayanır. MSM sendromu daha az anlaşılan ve bildirilen sendromdur. Hasta çeşitli semptomlar gösterebilir. HOFI'nin MSM'nin bir paterni olduğu akılda tutulmalıdır.Radyolojik raporlamada bu nedenle HOFI varlığını ve derecesini belirtmek önem teşkil eder. Anahtar kelimeler: Morgagni-Stewart-Morel sendromu; hiperostozis frontalis internaCorresponding author * : Emrah Doğan,

Morgagni-Stewart-Morell syndrome presenting with neurological symptoms: a case report

“…In 1930, Morel reported the first living case. MSM syndrome presents with endocrinological, metabolic, and neuropsychiatric symptoms [1][2][3][4][5].…”

“…The patient was a 76-year-old female. Although the pathophysiology of MSM syndrome has not been clearly determined, it is believed to be related to long-term exposure to estrogen, obesity, high leptin levels, and genetics [3,4]. Genetic transmission is believed to Treatment of MSM syndrome is symptom-based and usually includes weight-control medications, as well as diet and lifestyle changes.…”

“…The mean age of onset is 45 years. Reported cases in literature are predominantly women [ 1 – 3 ]. The patient was a 76-year-old female.…”

“…Morgagni-Stewart-Morel (MSM) syndrome is characterized by the thickening of the frontal bone of the skull (hyperostosis frontalis interna), obesity, neurological symptoms, and hypertrichosis [1][2][3]. In addition, diabetes, hyperparathyroidism, and other endocrine problems may accompany this condition.…”