The multidetector CT evaluation of diffuse hyperostosis frontalis interna

Abstract

OBJECTIVES. Hyperostosis frontalis interna (HFI) is a condition that involves the non-cancerous growth of the inner part of the frontal bone. We investigated diffuse HFI in cranial CT in terms of bone thickness and density. MATERIAL AND METHODS. The cranial CT images of 154 adult patients with diffuse HFI and 151 adult patients without HFI were included in the study. Bone thickness measurements were performed at vertex, frontal tuberosity and frontal sinus levels in the midline, right and left lateral parts. Density measurements were also performed in the same areas. In the HFI group, measurements were performed at the HFI and non-HFI regions. In the control group, density measurements were also performed. RESULTS. HFI was detected more in females (96.1%). In diffuse HFI patients, bone thickness values increased at the vertex, frontal tuberosity and frontal sinus levels (p<0.05). Bone densities of the HFI parts increased at vertex and frontal tuberosity levels (p<0.05). In the HFI group, there were positive correlations between bone thicknesses (p<0.05). As bone thicknesses increased, bone density values decreased (p<0.05). In older patients, frontal tuberosity and frontal sinus bone densities decreased (p<0.05). CONCLUSION. HFI may be one of the reasons for headaches in females. In the future, it would be better to investigate the relationship between HFI and headaches. The physicians should notice that increased bone thickness may be the sign of the HFI and they should consult with the Radiology Department. When HFI is detected, an endocrinological assessments will also be performed.