Morbidity and growth of infants and young children in a rural Mexican village.

Condon-Paoloni, Deanne; Cravioto, J; Johnston, Francis E.; Licardie, E R De; Scholl, Theresa O.

doi:10.2105/ajph.67.7.651

Cited by 53 publications

(18 citation statements)

References 24 publications

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“… 17,18 Indeed, these and our subsequent studies suggested that diarrheal illnesses in the first 1–2 years of life may account for a persisting 4 cm shortfall of growth (∼8.2 cm when the effects of intestinal helminths in just the first 2 years of life are included) 19,20 . Similar findings of an important impact of diarrhea on childhood growth have been made in Guatemala, West Africa, Mexico, and Bangladesh 21–26 . When challenged by the argument that catch‐up growth reverses the growth impairment of isolated diarrheal illnesses, 27 analyses of weight gains following a diarrheal illness in our studies in Brazil revealed that recurrent diarrhea reduced weight and, albeit less significantly, height gains by 48% and 21%, respectively, when compared with children who did not have recurrent diarrhea 17,18,28,29 (Table 1).…”

Section: Enteric Infections and Malnutrition: A Vicious Cyclementioning

confidence: 72%

Malnutrition as an enteric infectious disease with long-term effects on child development

et al. 2008

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Malnutrition is a major contributor to mortality and is increasingly recognized as a cause of, potentially lifelong, functional disability. Yet, a rate-limiting step in achieving normal nutrition may be impaired absorptive function due to multiple repeated enteric infections. This is especially problematic in children whose diets are marginal. In malnourished individuals, the infections are even more devastating. This review documents the evidence that intestinal infections lead to malnutrition and that malnutrition worsens intestinal infections. The clinical data presented here derive largely from long-term cohort studies that are supported by controlled animal studies. Also reviewed are the mechanisms by which enteric infections lead to undernutrition and by which malnutrition worsens enteric infections, with implications for potential novel interventions. Further intervention studies are needed to document the relevance of these mechanisms and, most importantly, to interrupt the vicious diarrhea-malnutrition cycle so children may develop their full potential.

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Section: Enteric Infections and Malnutrition: A Vicious Cyclementioning

confidence: 72%

Malnutrition as an enteric infectious disease with long-term effects on child development

et al. 2008

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“…Studies on children have shown an association between the level of bacterial contamination of food and post weaning growth rates (Martorell et al, 1975;Condon-Paoloni et al, 1977;Coates, 1980;Bairagi et al, 1987;Cebu Study Team, 1991;Cebu Study Team, 1992;Walker et al, 1992;Adair et al, 1993). Similar studies in animals have indicated that feeding neonates with diets low in bacteria led to a lower incidence of gastrointestinal disorders and improvement in growth compared with animals that received diets with higher levels of bacterial contamination (Coates, 1980;Speck, 1983;Black et al, 1984b).…”

Section: Introductionmentioning

confidence: 99%

Effect of preweaning feeding of pasteurized and nonpasteurized milk on postweaning weight gain of heifer calves on a Californian dairy

Jamaluddin

Hird

Thurmond

et al. 1996

Preventive Veterinary Medicine

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The effect of preweaning feeding of pasteurized colostrum and pasteurized waste milk on postweaning performance of dairy heifers on a dairy in the Central Valley of California was investigalzd as an extension of a clinical trial examining the effect of preweaning growth and morbidity on performance at weaning. Of the 1.50 heifer calves originally enrolled in the field trial, 115 calves (59 treatment, 56 controls) were followed to about 6 months of age, during which time their weights were measured. After weights were adjusted for several potential risk factors and effect modifiers, calves fed pasteurized colostrum and pasteurized waste milk were 3.7 kg heavier at 180 days of age than those fed nonpasteurized colostrum and nonpasteurized milk.

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“…Most of the studies which have asserted that children born earlier in a family's reproductive period are healthier than those born later are based on small crosssectional samples where the individuals have not been systematically re-studied (Condon-Paoloni et at, 1977;Horton, 1988). Furthermore, since most of these studies compared individuals with their own siblings the low birth order individuals were systematically older and members of an earlier cohort than those of higher birth order.…”

Section: Introductionmentioning

confidence: 99%