Montreal Cognitive Assessment and Mini-Mental State Examination performance in patients with mild-to-moderate dementia with Lewy bodies, Alzheimer's disease, and normal participants in Taiwan

Abstract

The MoCA is a more sensitive instrument than the MMSE to screen AD or DLB patients from non-dementia cases.

Alzheimer's disease cerebrospinal fluid biomarkers predict cognitive decline in lewy body dementia

“…However, analyses including only those without treatment showed similar findings as the overall analysis, indicating that treatment status is not a major confounder. MMSE was used as the measure of cognition, which is less sensitive to the early cognitive changes in PD and perhaps also DLB, than other scales such as the Montreal Cognitive Assessment (MoCA) . However, our recent analysis suggests that MMSE and MoCA are equally sensitive to the cognitive change in DLB, as has been shown also in PD .…”

Multicenter Validation of an MMSE‐MoCA Conversion Table

“…Moreover, executive subtests—most notably verbal fluency, but also trail‐making and clock drawing—can be discouraging to patients with severe cognitive deficits, hence clinicians instinctively chose easier tests like the MMSE in this population. Nonetheless, multiple studies have shown that the MoCA in fact does not have a significant floor effect even in moderate to advanced stages of dementia …”

The prognosis of dementia with Lewy bodies

“…16,17 . However, the sensitivity to change in DLB has been reported to be similar in MoCA and MMSE 18 .…”