Monophasic and Diphasic Action Potentials of the Stomach

Ichikawa, Santa; Bozler, Emil

doi:10.1152/ajplegacy.1955.182.1.92

Cited by 29 publications

(7 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The pattern of spontaneous electrical activities of the antrum muscle fibers was similar to those of mammalian stomach muscles recorded by previous investiga tors (Ichikawa and Bozler 1955;Papasova et al 1968;Bortoff and Davis 1968;Fujii 1971), particularly those recorded intracellularly (Kuriyama et al . 1970;Ito and Kuriyama 1975).…”

Section: Discussionsupporting

confidence: 79%

Non-adrenergic Inhibition of the Electrical Activity of the Antrum Muscle Fibers of the Guinea-Pig Stomach

Ohkawa

Watanabe

1976

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 79%

Non-adrenergic Inhibition of the Electrical Activity of the Antrum Muscle Fibers of the Guinea-Pig Stomach

Ohkawa

Watanabe

1976

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

“…†P Ͻ 0.05, pacemaker area or antrum compared with fundus or corpus (Tukey). It is important to note that the extracellular recording technique used in this study only records the extracellular current generated by the depolarization of the slow wave potential and does not record the plateau nor the repolarization phase of the slow wave (4,5,17). Furthermore, because the dimension of the electrode tip (0.3 mm diameter) is quite large compared with the size of the cells, the potentials recorded are the sum of the depolarization of hundreds of cells in the recorded region.…”

Section: Methodsmentioning

confidence: 99%

Origin and propagation of the slow wave in the canine stomach: the outlines of a gastric conduction system

Lammers¹,

Donck²,

Stephen³

et al. 2009

American Journal of Physiology-Gastrointestinal and Liver Physi

115

178

View full text Add to dashboard Cite

Slow waves are known to originate orally in the stomach and to propagate toward the antrum, but the exact location of the pacemaker and the precise pattern of propagation have not yet been studied. Using assemblies of 240 extracellular electrodes, simultaneous recordings of electrical activity were made on the fundus, corpus, and antrum in open abdominal anesthetized dogs. The signals were analyzed off-line, pathways of slow wave propagation were reconstructed, and slow wave velocities and amplitudes were measured. The gastric pacemaker is located in the upper part of the fundus, along the greater curvature. Extracellularly recorded slow waves in the pacemaker area exhibited large amplitudes (1.8 +/- 1.0 mV) and rapid velocities (1.5 +/- 0.9 cm/s), whereas propagation in the remainder of the fundus and in the corpus was slow (0.5 +/- 0.2 cm/s) with low-amplitude waveforms (0.8 +/- 0.5 mV). In the antrum, slow wave propagation was fast (1.5 +/- 0.6 cm/s) with large amplitude deflections (2.0 +/- 1.3 mV). Two areas were identified where slow waves did not propagate, the first in the oral medial fundus and the second distal in the antrum. Finally, recordings from the entire ventral surface revealed the presence of three to five simultaneously propagating slow waves. High resolution mapping of the origin and propagation of the slow wave in the canine stomach revealed areas of high amplitude and rapid velocity, areas with fractionated low amplitude and low velocity, and areas with no propagation; all these components together constitute the elements of a gastric conduction system.

show abstract

“…Conduction can take place across many cell lengths, but the velocity is very slow compared to that of other excitable tissues (Biilbring et al 1958). There is evidence that sites of low electrical resistance exist between the cells (Ichikawa & Bozler, 1955;Prosser & Sperelakis, 1956;Bulbring et al 1958), but neither the passive properties of the membrane, nor the nature of the intercell connexion are yet known. However, by analogy with synapses, where electrical transmission is believed to occur (Fatt, 1954), it has been suggested that conduction may be expected to depend partly on the properties of the region of contact between adjacent cells, and partly on the excitability of the cells involved (Biilbring et at.…”

Section: -2mentioning

confidence: 99%

The effects of acetylcholine on membrane potential, spike frequency, conduction velocity and excitability in the taenia coli of the guinea‐pig

Burnstock¹

1958

The Journal of Physiology

View full text Add to dashboard Cite

Monophasic and Diphasic Action Potentials of the Stomach

Cited by 29 publications

References 1 publication

Non-adrenergic Inhibition of the Electrical Activity of the Antrum Muscle Fibers of the Guinea-Pig Stomach

Non-adrenergic Inhibition of the Electrical Activity of the Antrum Muscle Fibers of the Guinea-Pig Stomach

Origin and propagation of the slow wave in the canine stomach: the outlines of a gastric conduction system

The effects of acetylcholine on membrane potential, spike frequency, conduction velocity and excitability in the taenia coli of the guinea‐pig

Contact Info

Product

Resources

About