“…When a plastic housing, such as polypropylene (PP) or cyclic olefin copolymer (COC), is used then the surface attachment to the housing is somewhat more challenging due to the hydrophobicity and low reactivity of polyolefines. PP is particularly popular as a housing for polymer monoliths in SPE applications and formats have included pipette-tips [2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20] and syringe filters [21]. These monoliths have been used for the pre-concentration of peptides [2,8,10,11,15,16,18], proteins [5,20], fungicides [12], pesticides [3,4], plant flavones [7], pharmaceuticals [6,9,13,14,17] alkaloids [19], and metals [21] and fabrication protocols using pipette-tips have been reviewed by Blomberg [21] and Altun [22].…”