Monolith dip-it: a bifunctional device for improving the sensitivity of direct analysis in real time mass spectrometry

Li, Xianjiang; Li, Ze; Wang, Xin; Zhang, Yiding; Bai, Yu; Liu, Huwei

doi:10.1039/c6an00839a

Cited by 20 publications

(10 citation statements)

References 28 publications

(28 reference statements)

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“…After filled with the mixture, the dip‐it was kept at 60°C in oven for 20 h. After polymerization, the tip of white monolith dip‐it was immersed into HF solution with 2 mm for 2 h. After this treatment, the outer glass of the dip‐it was corroded and inner monolith was exposed. Then, the monolithic tip was rinsed with methanol in a vial to remove porogen solvent and unreacted monomers .…”

Section: Methodsmentioning

confidence: 99%

Fast analysis of glycosides based on HKUST-1-coated monolith solid-phase microextraction and direct analysis in real-time mass spectrometry

Wang

et al. 2017

J. Sep. Sci.

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Glycosides are a kind of highly important natural aromatic precursors in tobacco leaves. In this study, a novel HKUST-1-coated monolith dip-it sampler was designed for the fast and sensitive analysis of trace glycosides using direct analysis in real-time mass spectrometry. This device was prepared in two steps: in situ polymerization of monolith in a glass capillary of dip-it and layer-by-layer growth of HKUST-1 on the surface of monolith. Sufficient extraction was realized by immersing the tip to solution and in situ desorption was carried out by plasma direct analysis in real time. Compared with traditional solid-phase microextraction protocols, sample desorption was not needed anymore, and only extraction conditions were needed to be optimized in this method, including the gas temperature of direct analysis in real time, extraction time, and CH COONH additive concentration. This method enabled the simultaneous detection of six kinds of glycosides with the limits of detection of 0.02-0.05 μg/mL and the linear ranges covering two orders of magnitude with the limits of quantitation of 0.05-0.1 μg/mL. Moreover, the developed method was applied for the glycosides analysis of three tobacco samples, which only took about 2 s for every sample.

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Section: Methodsmentioning

confidence: 99%

Fast analysis of glycosides based on HKUST-1-coated monolith solid-phase microextraction and direct analysis in real-time mass spectrometry

Wang

et al. 2017

J. Sep. Sci.

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“…Some strategies have been developed to enhance the chemical sensitivity of DART‐MS. For instance, Liu and coworkers established a bifunctional monolith dip‐it that can be used as an SPME device coupled with DART‐MS to improve the sensitivity of DART‐MS 18 . This technique has been applied for the analysis of four Sudan dyes in chili powder.…”

Section: Applications Of Dart‐ms In Different Types Of Foodsmentioning

confidence: 99%

Applications of direct analysis in real time mass spectrometry in food analysis: A review

Zhang

Ren

Chingin

2021

Rapid Comm Mass Spectrometry

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Rationale Direct analysis in real time (DART) combined with mass spectrometry (MS) detection has become one of the most broadly used analytical approaches for the direct molecular characterization of food samples with regard to their chemical quality, safety, origin, and authentication. The major advantages of DART‐MS for food analysis include high chemical sensitivity and specificity, high speed and throughput of analysis, simplicity, and the obviation of tedious sample preparation and solvents. Methods The recent applications of DART coupled with different mass analyzers, including quadrupole, ion trap, Orbitrap, and time of flight, are discussed. In addition, sample pretreatment methods that have been coupled with DART‐MS are discussed. Results We summarize the applications of DART‐MS in food science and industry published in the period from 2005 to this date. The applications and analytical characteristics are systematically categorized across the three major types of foods: solid foods, liquid foods, and viscous foods. Conclusions DART‐MS has proved its high suitability for the direct, rapid, and high‐throughput molecular analysis of very different food samples with minimal or no sample preparation, thus offering a high‐speed alternative to liquid chromatography/mass spectrometry (LC/MS) and gas chromatography/mass spectrometry (GC/MS) approaches that are traditionally employed in food analysis.

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“…Various contaminants were determined by SPME technique in other food commodities (Table 2), such as milk [29,[177][178][179][180][181][182], fish [183][184][185][186][187], honey [188][189][190], tea [191][192][193], coffee [194,195], oil [196,197], butter [198], rice [199], chili [166,200,201], and seaweeds [202]. In particular, in milk SPME has been exploited in different coatings.…”

Section: Other Foodsmentioning

confidence: 99%

“…After extraction, the carbon nanotube film was attached to the front end of a glass capillary, and then transferred to the visible plasma beam of the DCBI source for surface desorption/ionization of the enriched analytes for MS analysis. In another application, the coupling of SPME with ambient mass spectrometry was again proposed for the analysis of Sudan dyes in chili powder [201]. In this case, a bifunctional monolith dip-it, prepared by in situ polymerization of poly(BMA-EDMA-MAA) monolith in the glass capillary of dip-it, was used as an SPME device for direct analysis in real-time mass spectrometry (DART-MS).…”

Section: Other Foodsmentioning

confidence: 99%

Recent Applications and Newly Developed Strategies of Solid-Phase Microextraction in Contaminant Analysis: Through the Environment to Humans

Naccarato

Tagarelli

2019

Separations

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The present review aims to describe the recent and most impactful applications in pollutant analysis using solid-phase microextraction (SPME) technology in environmental, food, and bio-clinical analysis. The covered papers were published in the last 5 years (2014–2019) thus providing the reader with information about the current state-of-the-art and the future potential directions of the research in pollutant monitoring using SPME. To this end, we revised the studies focused on the investigation of persistent organic pollutants (POPs), pesticides, and emerging pollutants (EPs) including personal care products (PPCPs), in different environmental, food, and bio-clinical matrices. We especially emphasized the role that SPME is having in contaminant surveys following the path that goes from the environment to humans passing through the food web. Besides, this review covers the last technological developments encompassing the use of novel extraction coatings (e.g., metal-organic frameworks, covalent organic frameworks, PDMS-overcoated fiber), geometries (e.g., Arrow-SPME, multiple monolithic fiber-SPME), approaches (e.g., vacuum and cold fiber SPME), and on-site devices. The applications of SPME hyphenated with ambient mass spectrometry have also been described.

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Monolith dip-it: a bifunctional device for improving the sensitivity of direct analysis in real time mass spectrometry

Cited by 20 publications

References 28 publications

Fast analysis of glycosides based on HKUST-1-coated monolith solid-phase microextraction and direct analysis in real-time mass spectrometry

Fast analysis of glycosides based on HKUST-1-coated monolith solid-phase microextraction and direct analysis in real-time mass spectrometry

Applications of direct analysis in real time mass spectrometry in food analysis: A review

Recent Applications and Newly Developed Strategies of Solid-Phase Microextraction in Contaminant Analysis: Through the Environment to Humans

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