Monodispersed Gold Nanorod‐Embedded Silica Particles as Novel Raman Labels for Biosensing

Abstract

Biocompatible, photostable, and multiplexing‐compatible surface‐enhanced Raman spectroscopic tagging materials have been developed that are composed of gold nanorod (GNR)‐embedded silica particles and organic Raman labels. GNR‐embedded silica particles were prepared with different surface coverage by the assembly of GNRs on silica particles based on an electrostatic interaction and subsequent coating of silica with controllable thickness. This method allows the incorporation of various organic Raman labels to generate intense surface‐enhanced Raman scattering (SERS) spectra. Furthermore, SERS‐active particles are demonstrated as novel Raman tags for immunoassay. The results suggest SERS tags can be used for multiplex and ultrasensitive detection of biomolecules.

Preparation and Multiple Antitumor Properties of AuNRs/Spinach Extract/PEGDA Composite Hydrogel

“…The curve in Figure C exhibits a two-stage temperature variation: a rapid temperature increase (∼0.48 °C/min) during the first 10 min, followed by a slow temperature increase (∼0.061 °C/min) from 10 to 40 min. This result further confirms that AuNRs have a good photothermal effect, as described in ref .…”

Fabrication of Au nanorod‐coated Fe3O4 microspheres as SERS substrate for pesticide analysis by near‐infrared excitation

“…A and B, the TEM images also indicated that the Fe 3 O 4 microspheres were coated with NRs. This is because, as previously mentioned, Au NRs employed in this work were pretreated with PVP and the surface was negatively charged, while the surfaces of amino‐functionalized Fe 3 O 4 microspheres were positively charged due to a large number of basic amino groups at the polymer chains of PEI, thus making the assembly of Au NRs on the surfaces of Fe 3 O 4 microspheres based on the electrostatic interaction. In order to further investigate the elemental distribution of the composite, the elemental mappings of O, Fe, and Au were also performed by EDS area scans corresponding to Fig.…”

Enhanced Fluorescence of Quantum Dots by Au Nanoparticles on Multi-Color Silica Spheres Labeled with Organic Dyes and Quantum Dots

“…In present work, when the FITC-SiO 2 @QDs spheres are incubated with the Au NPs, Au NPs would attach to the surface of FITC-SiO 2 @QDs through the strong binding interaction between the Au NPs and the residual amino groups [21][22][23][24]. The intensity of FITC in FITC-SiO 2 @QDs would not be influenced obviously, because the great mass of FITC has been embedded in the interior of silica spheres and the distances from the FITC to the Au NPs are too far.…”