Monodispersed Gold Nanorod‐Embedded Silica Particles as Novel Raman Labels for Biosensing

Wang, Chungang; Chen, Ying; Wang, Tingting; Ma, Zhanfang; Su, Zhong‐Min

doi:10.1002/adfm.200700503

Cited by 119 publications

(92 citation statements)

References 38 publications

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“…One thing should also be pointed out is that silver nanoparticle or silver-coated gold nanoparticle show 10-10 2 times stronger enhancement due to a stronger molar extinction coefficient [323] and less plasmon damping compared to gold. Nanorod aggregation, [327][328][329] two-dimensional film, [330][331][332][333] and assembly, especially end-to-end assembly, [229] offer further enhancement due to plasmon coupling between particles. In the recent studies by Huang et al, [334] the assembly of gold nanorods by cancer cells due to the binding of the anti-EGFR-conjugated rods to the overexpressed EGFR (epidermal growth factor receptor) on the cancer cell surface gives highly enhanced, sharp, and polarized SERS, while no SERS is observed from the majority of the normal cells.…”

Section: Surface-enhanced Raman Scattering Molecular Sensingmentioning

confidence: 99%

Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications

2009

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Noble metal nanoparticles are capable of confining resonant photons in such a manner as to induce coherent surface plasmon oscillation of their conduction band electrons, a phenomenon leading to two important properties. Firstly, the confinement of the photon to the nanoparticle's dimensions leads to a large increase in its electromagnetic field and consequently great enhancement of all the nanoparticle's radiative properties, such as absorption and scattering. Moreover, by confining the photon's wavelength to the nanoparticle's small dimensions, there exists enhanced imaging resolving powers, which extend well below the diffraction limit, a property of considerable importance in potential device applications. Secondly, the strongly absorbed light by the nanoparticles is followed by a rapid dephasing of the coherent electron motion in tandem with an equally rapid energy transfer to the lattice, a process integral to the technologically relevant photothermal properties of plasmonic nanoparticles. Of all the possible nanoparticle shapes, gold nanorods are especially intriguing as they offer strong plasmonic fields while exhibiting excellent tunability and biocompatibility. We begin this review of gold nanorods by summarizing their radiative and nonradiative properties. Their various synthetic methods are then outlined with an emphasis on the seed-mediated chemical growth. In particular, we describe nanorod spontaneous self-assembly, chemically driven assembly, and polymer-based alignment. The final section details current studies aimed at applications in the biological and biomedical fields.

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Section: Surface-enhanced Raman Scattering Molecular Sensingmentioning

confidence: 99%

Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications

2009

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“…93,118,153 Wang and colleagues used goat anti-hIgG and hIgG as a model system for protein detection. 118 A substrate coated with goat anti-hIgG was exposed to a solution containing different concentrations of hIgG. After incubation, the sample was immersed into a solution of goat anti-hIgG-anchored, Au NR-embedded, silica SERS tags.…”

Section: 149mentioning

confidence: 99%

SERS Tags: Novel Optical Nanoprobes for Bioanalysis

2012

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“…In recent years, gold nanorods (GNRs) have attracted considerable attention for their unique properties in localized photothermal therapy [19,20], biosensing [21], and molecular imaging [22]. Particularly, being an anisotropic, rod-shaped nanomaterial that is easily functionalized, GNR has begun to attract significant research interest in gene delivery [7,[23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Efficient RNA delivery by integrin-targeted glutathione responsive polyethyleneimine capped gold nanorods

et al. 2015

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Guo, S., Efficient RNA delivery by integrin-targeted glutathione responsive polyethyleneimine capped gold nanorods, Acta Biomaterialia (2015), doi: http://dx.doi.org/10.1016/j.actbio. 2015.05.028 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. targeting, intracellular glutathione-triggered "off-on" release and endosomal escape, the RDG nanocarrier developed herein appears to be a highly promising non-viral vector for efficient RNAi.

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Monodispersed Gold Nanorod‐Embedded Silica Particles as Novel Raman Labels for Biosensing

Cited by 119 publications

References 38 publications

Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications

Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications

SERS Tags: Novel Optical Nanoprobes for Bioanalysis

Efficient RNA delivery by integrin-targeted glutathione responsive polyethyleneimine capped gold nanorods

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