Monkeypox vaccination: Does it cause neurologic and psychiatric manifestations? – Correspondence

Farahat, Ramadan Abdelmoez; Shrestha, Abhigan Babu; El-Sayed, Mohamed A.; Memish, Ziad A.

doi:10.1016/j.ijsu.2022.106926

Cited by 6 publications

(7 citation statements)

References 22 publications

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“…The latter is not preferable due to the higher risk of adverse reactions. The MVA vaccine has an excellent safety profile and is indicated even in immunocompromised persons against MPOX and smallpox with two doses, four weeks apart [ 37 , 41 , 42 ].…”

Section: Reviewmentioning

confidence: 99%

The 2022 Monkeypox Epidemic and What Has Led to the Current State of the Disease in the US: A Systematic Review

Chaudhari¹,

Treffeisen²,

Virk³

et al. 2023

Cureus

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Monkeypox virus (MPOX) is a zoonotic disease in humans. It is similar genetically to its virus family member, smallpox. This virus has been studied since the 1970s. The virus remains endemic to the Congo and West African regions, but non-endemic spreads have been cited. The most recent non-endemic outbreak in the spring of 2022 amidst the current COVID-19 pandemic is of interest due to its impact on global medical, economic, and societal climates. This literature review aims to highlight the virology, clinical signs and symptoms, diagnosis, prevention, and treatment of MPOX and discuss the social implications of the recent 2022 outbreak.We hope this review can pinpoint important clinical pearls of the MPOX virus and its societal impacts to further promote important discussion of this virus and its disease.

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Section: Reviewmentioning

confidence: 99%

The 2022 Monkeypox Epidemic and What Has Led to the Current State of the Disease in the US: A Systematic Review

Chaudhari¹,

Treffeisen²,

Virk³

et al. 2023

Cureus

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“…We gave values between 0 and 3 to the following frequency categories: never, 140 sometimes, often, and very frequently. GAD7 scores were tallied and classified as minimal (0-4), mild (5)(6)(7)(8)(9), moderate (10)(11)(12)(13)(14) The Syrian Ethical Society for Scientific Research provided its stamp of approval (SA-AL4853B). Furthermore, at least one ethical approval was taken from each inquired country in our study.…”

Section: Generalized Anxiety Disorder (Gad) Toward Monkeypoxmentioning

confidence: 99%

“…Psychiatric and neurological manifestations might also occur [8]. In most situations, monkeypox infections heal without medical treatment.…”

Section: Introductionmentioning

confidence: 99%

Monkeypox Post COVID19: Knowledge, Worrying, and Vaccine Adoption of the Arabic General Population

Swed

Bohsas

Alibrahim

et al. 2022

Preprint

Self Cite

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Background: The outbreak of monkeypox was designated a global public health emergency by the World Health Organization on July 23, 2022. There have been more reported 60000 cases worldwide, most of which are in places where monkeypox has never been seen due to the travel of people who have the virus. This research aims to evaluate the Arabic general population on monkeypox disease, fears, and vaccine adoption after the WHO proclaimed a monkeypox epidemic and to compare these attitudes to those of the COVID-19 pandemic. Methods: This cross-sectional study was performed in some Arabic countries (Syria, Egypt, Qatar, Yemen, Jordan, Sudan, Algeria, and Iraq) between August 18 and September 7, 2022 to examine the Arabic people perspectives on monkeypox disease, fears, and vaccine adoption and to compare these attitudes to those of the COVID-19 pandemic. The inclusion criteria were the general public residing in Arabic nations and older than 18. This questionnaire has 32 questions separated into three sections: sociodemographic variables, prior COVID-19 exposure, and COVID-19 vaccination history. The second portion assesses knowledge and anxieties about monkeypox, while the third section includes the generalized anxiety disorder (GAD7) scale. Logistic regression analysis were performed to compute the adjusted odds ratios (aOR), and their confidence intervals (95%CI) using STATA (version 17.0) Results: A total of 3665 respondents from 17 Arabic countries were involved in this study. Almost two third (n= 2427, 66.2%) of participants expressed more worried about COVID -19 than monkeypox diseases. Regarding the major cause for concern about monkeypox, 39.5% of participants attributed their anxiety they or a member of their family may contract the illness, while 38.4% were concerned about another worldwide pandemic of monkeypox. According to the GAD 7 score, 71.7% of respondents showed very low anxiety toward monkeypox. 43.8% of the participants scored poor levels of knowledge about monkeypox disease. Participants with previous COVID-19 infection showed greater acceptance to receive the monkeypox vaccine 1.206 times than those with no previous infection. A higher concern for the monkeypox than COVID-19 was shown by the participants who perceived monkeypox as dangerous and virulent 3.097 times than those who didn’t. Participants who have a chronic disease (aOR: 1.32; 95%CI: 1.09-1.60); participants worried about monkeypox (aOR: 1.21; 95%CI: 1.04-1.40); and perceived monkeypox as a dangerous and virulent disease (aOR: 2.25; 95%CI: 1.92-2.65); and excellent knowledge level (aOR: 2.28; 95%CI: 1.79-2.90) have emerged as significant predictors. Conclusion: Our study reported that three fourth of the participants were more concerned about COVID-19 than monkeypox disease. As well, most of the participants have inadequate levels of knowledge regarding monkeypox disease. Hence immediate action should be taken to address this problem. Consequently, it is crucial to learn about monkeypox and spread information about its prevention.

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“…This disease has been linked to several complications, including bacterial superinfection of the skin, pneumonia, encephalitis, sepsis, and death [7]. Psychiatric and neurological manifestations might also occur [8]. In most cases, monkeypox infections heal without medical treatment.…”

Section: Introductionmentioning

confidence: 99%

Monkeypox Post-COVID-19: Knowledge, Worrying, and Vaccine Adoption in the Arabic General Population

et al. 2023

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Background: The outbreak of monkeypox was declared a global public health emergency by the World Health Organization on 23 July 2022. There have been 60,000 cases reported worldwide, most of which are in places where monkeypox has never been seen due to the travel of people who have the virus. This research aims to evaluate the general Arabic population in regard to the monkeypox disease, fears, and vaccine adoption after the WHO proclaimed a monkeypox epidemic and to compare these attitudes to those of the COVID-19 pandemic. Methods: This cross-sectional study was performed in some Arabic countries (Syria, Egypt, Qatar, Yemen, Jordan, Sudan, Algeria, and Iraq) between 18 August and 7 September 2022. The inclusion criteria were the general public residing in Arabic nations and being older than 18. This questionnaire has 32 questions separated into three sections: sociodemographic variables, prior COVID-19 exposure, and COVID-19 vaccination history. The second portion assesses the knowledge and anxieties about monkeypox, while the third section includes the generalized anxiety disorder (GAD7) scale. Logistic regression analyses were performed to compute the adjusted odds ratios (aOR) and their confidence intervals (95%CI) using STATA (version 17.0). Results: A total of 3665 respondents from 17 Arabic countries were involved in this study. Almost two-thirds (n = 2427, 66.2%) of the participants expressed more worry about COVID-19 than monkeypox diseases. Regarding the major cause for concern about monkeypox, 39.5% of participants attributed their anxiety to the fear that they or a member of their family may contract the illness, while 38.4% were concerned about monkeypox becoming another worldwide pandemic. According to the GAD 7 score, 71.7% of the respondents showed very low anxiety toward monkeypox and 43.8% of the participants scored poor levels of knowledge about monkeypox disease. Participants with previous COVID-19 infection showed a 1.206 times greater acceptance to receive the monkeypox vaccine than those with no previous infection. A 3.097 times higher concern for monkeypox than COVID-19 was shown by the participants who perceived monkeypox as dangerous and virulent than those who did not. Participants who have a chronic disease (aOR: 1.32; 95%CI: 1.09–1.60); participants worried about monkeypox (aOR: 1.21; 95%CI: 1.04–1.40), and perceived monkeypox as a dangerous and virulent disease (aOR: 2.25; 95%CI: 1.92–2.65); and excellent knowledge level (aOR: 2.28; 95%CI: 1.79–2.90) have emerged as significant predictors. Conclusions: Our study reported that three-fourths of the participants were more concerned about COVID-19 than monkeypox disease. In addition, most of the participants have inadequate levels of knowledge regarding monkeypox disease. Hence, immediate action should be taken to address this problem. Consequently, learning about monkeypox and spreading information about its prevention is crucial.

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Monkeypox vaccination: Does it cause neurologic and psychiatric manifestations? – Correspondence

Cited by 6 publications

References 22 publications

The 2022 Monkeypox Epidemic and What Has Led to the Current State of the Disease in the US: A Systematic Review

The 2022 Monkeypox Epidemic and What Has Led to the Current State of the Disease in the US: A Systematic Review

Monkeypox Post COVID19: Knowledge, Worrying, and Vaccine Adoption of the Arabic General Population

Monkeypox Post-COVID-19: Knowledge, Worrying, and Vaccine Adoption in the Arabic General Population

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