Monitoring the HIV continuum of care in key populations across Europe and Central Asia

Brown, AE; K, Attawell; Hales, Derek; Rice, Brian; Pharris, Anastasia; Supervie, Virginie; Beckhoven, Dominique Van; Delpech, Valérie; Heiden, Matthias an der; Marcus, Ulrich; Malý, Marek; Noori, Teymur

doi:10.1111/hiv.12603

Cited by 22 publications

(20 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Non‐Western European migrants, either from SSA or from another country, had the lowest percentages of cART initiation, as previously shown . Despite an improvement across the different key populations over time, cART initiation was still lower in migrants than in non‐migrants in France in 2016 .…”

Section: Discussionmentioning

confidence: 99%

Does region of origin influence the timing and outcome of first‐line antiretroviral therapy in France?

Gatey

Brun²,

Hamet³

et al. 2018

HIV Medicine

View full text Add to dashboard Cite

Objectives The aim of the study was to assess whether the timing of combination antiretroviral therapy (cART) initiation, the choice of cART and virological response differ in migrants versus European natives in the north and east of Paris area, after dissemination of French recommendations for universal treatment. Methods Antiretroviral therapy‐naïve HIV‐1‐infected adults with at least two follow‐up visits at one of 15 participating centres between 1 January 2014 and 31 March 2015 were included in the study. Factors associated with cART initiation before 31 March 2015, with protease inhibitor (PI)‐containing cART among individuals initiating cART, and with 1‐year virological success after cART initiation were assessed using multivariable logistic regression models. Sex, age, region of origin [Western Europe, sub‐Saharan Africa (SSA) or other], HIV transmission group, baseline AIDS status, CD4 cell count and plasma viral load (VL), and hepatitis B and/or C virus infection were considered in the analyses. Results Among 912 individuals, only 584 (64%) started cART during the study period. After adjustment, migrants from SSA were half as likely to initiate cART and to have a subsequent virological response compared with individuals from Western Europe [adjusted odds ratio (aOR) 0.54; 95% confidence interval (CI) 0.36–0.82; and aOR 0.52; 95% CI 0.28–0.98, respectively]. PI‐containing cART was more frequently prescribed in migrants from SSA, in people with lower CD4 cell counts and in people with higher VL. Conclusions Even in the context of universal cART recommendations and of free access to care, migrants from SSA still have delayed access to cART and a lower virological response. Efforts are still necessary to provide immediate cART to all people living with HIV.

show abstract

Section: Discussionmentioning

confidence: 99%

Does region of origin influence the timing and outcome of first‐line antiretroviral therapy in France?

Gatey

Brun²,

Hamet³

et al. 2018

HIV Medicine

View full text Add to dashboard Cite

show abstract

“…EuroSIDA data is collected in a standardized manner at the individual level. This is in contrast to many existing studies (including surveillance data) that are the result of cross-sectional surveys often filled in by public health experts, or where data is merged from different data sources [2,11].…”

Section: Within-region Variation Between Transmission Categoriesmentioning

confidence: 98%

“…Some strengths of our study should be mentioned. While other studies have explored barriers to care for single key populations, this is one of few studies comparing differences between transmission categories in core HIV care parameters [6,7,11,27,28]. Furthermore, our study is among few European studies that hold some data on key populations, and is among the first to compare across regions of Europe [11,[29][30][31][32].…”

Section: Within-region Variation Between Transmission Categoriesmentioning

confidence: 99%

“…While other studies have explored barriers to care for single key populations, this is one of few studies comparing differences between transmission categories in core HIV care parameters [6,7,11,27,28]. Furthermore, our study is among few European studies that hold some data on key populations, and is among the first to compare across regions of Europe [11,[29][30][31][32]. Thirdly, our standardized data collection overcomes many of the problems, such as a lack of common definitions, often faced when trying to compare quality of care across countries [11,33].…”

Section: Within-region Variation Between Transmission Categoriesmentioning

confidence: 99%

“…Furthermore, our study is among few European studies that hold some data on key populations, and is among the first to compare across regions of Europe [11,[29][30][31][32]. Thirdly, our standardized data collection overcomes many of the problems, such as a lack of common definitions, often faced when trying to compare quality of care across countries [11,33]. EuroSIDA data is collected in a standardized manner at the individual level.…”

Section: Within-region Variation Between Transmission Categoriesmentioning

confidence: 99%

See 2 more Smart Citations

Variation in antiretroviral treatment coverage and virological suppression among three HIV key populations

Laut

Shepherd

Gottfreðsson

et al. 2018

Aids

View full text Add to dashboard Cite

Objectives: We assessed differences in antiretroviral treatment (ART) coverage and virological suppression across three HIV key populations, as defined by self-reported HIV transmission category: sex between men, injection drug use [IDU] and heterosexual transmission. Design: Multinational cohort study Methods: Within the EuroSIDA study, we assessed region-specific percentages of ART-coverage among those in care and virological suppression (<500 copies/mL) among those on ART, , and analyzed differences between transmission categories using logistic regression. Results: Among 12,872 participants followed 01/07/2014-30/06/2016, the percentages of ARTcoverage and virological suppression varied between transmission categories, depending on geographical region (global p for interaction: p=0.0148 for ART-coverage, p=0.0006 for virological suppression). In Western (adjusted odds ratio [aOR] 1.41 [95% confidence interval 1.14-1.75]) and Northern Europe (aOR 1.68 [1.25-2.26]) heterosexuals were more likely to receive ART than men who have sex with men (MSM), while in Eastern Europe there was some evidence that infection through IDU (aOR 0.60 [0.31-1.14]) or heterosexual contact (aOR 0.58 [0.30-1.10]) was associated with lower odds of receiving ART. In terms of virological suppression, people infected through IDU or heterosexual contact in East Central and Eastern Europe were around half as likely as MSM to have a suppressed viral load on ART, while we observed no differences in virological suppression across transmission categories in Western and Northern Europe. Conclusions: In our cohort, patterns of ART-coverage and virological suppression among key populations varied by geographical region, emphasizing the importance of tailoring HIV programmes to the local epidemic.

show abstract

Control of HIV/AIDS can be achieved with multi-strategies

Detels

2019

Global Health Journal

View full text Add to dashboard Cite

Monitoring the HIV continuum of care in key populations across Europe and Central Asia

Cited by 22 publications

References 41 publications

Does region of origin influence the timing and outcome of first‐line antiretroviral therapy in France?

Does region of origin influence the timing and outcome of first‐line antiretroviral therapy in France?

Variation in antiretroviral treatment coverage and virological suppression among three HIV key populations

Control of HIV/AIDS can be achieved with multi-strategies

Contact Info

Product

Resources

About