Monitoring of ion beam energy by tracking of secondary ions: First measurements in a patient-like phantom

Martišíková, M.; Jakůbek, J.; Gwosch, Klaus; Hartmann, B.; Telsemeyer, Julia; Pospı́šil, S.; Jäkel, Oliver

doi:10.1109/nssmic.2012.6551443

Cited by 4 publications

(4 citation statements)

References 13 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…they are mainly emitted in the direction of the primary carbon-ion beam, experimental configurations of secondary-ionbased monitoring methods use forward detection angles a with respect to the beam direction. Over the years, secondary-ions detection angles ranging from 0° (7,8) to 90° (9) were investigated. Most of the recently published experiments have been measured at either 30° (10,11), or at 60°and 90° (12)(13)(14).…”

Section: Introductionmentioning

confidence: 99%

Investigation of Suitable Detection Angles for Carbon-Ion Radiotherapy Monitoring in Depth by Means of Secondary-Ion Tracking

et al. 2021

View full text Add to dashboard Cite

The dose conformity of carbon-ion beam radiotherapy, which allows the reduction of the dose deposition in healthy tissue and the escalation of the dose to the tumor, is associated with a high sensitivity to anatomical changes during and between treatment irradiations. Thus, the monitoring of inter-fractional anatomical changes is crucial to ensure the dose conformity, to potentially reduce the size of the safety margins around the tumor and ultimately to reduce the irradiation of healthy tissue. To do so, monitoring methods of carbon-ion radiotherapy in depth using secondary-ion tracking are being investigated. In this work, the detection and localization of a small air cavity of 2 mm thickness were investigated at different detection angles of the mini-tracker relative to the beam axis. The experiments were conducted with a PMMA head phantom at the Heidelberg Ion-Beam Therapy Center (HIT) in Germany. In a clinic-like irradiation of a single field of 3 Gy (RBE), secondary-ion emission profiles were measured by a 2 cm2 mini-tracker composed of two silicon pixel detectors. Two positions of the cavity in the head phantom were studied: in front and in the middle of the tumor volume. The significance of the cavity detection was found to be increased at smaller detection angles, while the accuracy of the cavity localization was improved at larger detection angles. Detection angles of 20° – 30° were found to be a good compromise for accessing both, the detectability and the position of the air cavity along the depth in the head of a patient.

show abstract

Section: Introductionmentioning

confidence: 99%

Investigation of Suitable Detection Angles for Carbon-Ion Radiotherapy Monitoring in Depth by Means of Secondary-Ion Tracking

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Based on the encouraging results, a study of the method in an inhomogeneous phantom was initiated [6]. To simulate a patient head, a head phantom (Alderson Phantom, Radiology Support Devices Inc., USA) was used.…”

Section: B Non-invasive Monitoring Of the Beam In The Patientmentioning

confidence: 99%

“…The projection plane is defined as the vertical plane containing the beam axis. Image reprinted from [6].…”

Section: Beammentioning

confidence: 99%

See 1 more Smart Citation

Study of the capabilities of the Timepix detector for Ion Beam radiotherapy applications

Martišíková

Hartmann

Gwosch

et al. 2012

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)

Self Cite

View full text Add to dashboard Cite

The finite range of ion beams in matter and the presence of the Bragg-peak at the end of their range enable to create highly localized dose distributions. This advantage represents at the same time a challenge -namely to control all factors influencing the dose distribution with high precision.To ensure the required quality of the dose distribution applied to the patient, a number of measurement procedures is conducted.Many of these techniques were adopted from photon beam radiotherapy. Improvements in terms of the information amount gained are expected from new generations of dedicated ion detec tion techniques. One of the possible research directions is given by semiconductor-based detectors, which are at present rarely used in ion beam radiotherapy. In this contribution we report on the studies of the capabilities of the Timepix detector. This hybrid semiconductor pixelated detector was developed by the Medipix Collaboration at CERN. Its high spatial resolution allows an online registration of single ions. Experiments were performed at the Heidelberg Ion Beam Therapy Center in Germany using carbon ion beams. The signal pattern of single ions in the detector signal was shown to provide separation of the primary and different types of secondary ions. The direction of the secondary ions emerging from different irradiated phantoms were measured using 3D voxel detector containing several Timepix layers. The analysis of the recorded ion tracks shows a correlation with the beam range, position and width, which are all of high interest for monitoring of the beam within the patient during the therapy delivery. The results of the discussed studies show that the Timepix detector offers attractive capabilities for the needs of carbon ion beam therapy.

show abstract

Overview of current applications of the Timepix detector in spectroscopy, radiation and medical physics

Darwish

Marcu

Bezak

2019

Applied Spectroscopy Reviews

View full text Add to dashboard Cite

Monitoring of ion beam energy by tracking of secondary ions: First measurements in a patient-like phantom

Abstract: Due to the finite range of ions in matter and the presence of the Bragg-peak, ion beams provide highly localized dose distributions. In radiation therapy with ion beams, unpre

Cited by 4 publications

References 13 publications

Investigation of Suitable Detection Angles for Carbon-Ion Radiotherapy Monitoring in Depth by Means of Secondary-Ion Tracking

Investigation of Suitable Detection Angles for Carbon-Ion Radiotherapy Monitoring in Depth by Means of Secondary-Ion Tracking

Study of the capabilities of the Timepix detector for Ion Beam radiotherapy applications

Overview of current applications of the Timepix detector in spectroscopy, radiation and medical physics

Contact Info

Product

Resources

About