Monitoring of Changes in Selenium Concentration in Goat Milk During Short-Term Supplementation of Various Forms of Selenium

Pechová, Alena; Mišurová, Ľ.; Pavlata, L.; Dvořák, R.

doi:10.1007/s12011-007-8033-3

Cited by 30 publications

(20 citation statements)

References 24 publications

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“…Similar results were obtained by Salbe and Levander (1990). Similarly Pechova et al (2008) describe increased values of Se in the milk and whole blood of goats after supplementation in the form of yeast (Sel-Plex) where most of the element is present as Se-Met even if the animals are well saturated with this element. Selenium in this form is absorbed with higher efficiency by way of active transportation.…”

Section: Selenium Supplementation Experimentssupporting

confidence: 78%

“…These differences in results for the lactate-protein complex form could be down to the duration of the trial. Pechova et al (2008) carried out short experiments and the results were evaluated after only 20-day supplementation of Se to trial animals. Another factor that could have influenced the results in various experiments is the fact that animals included in the experiment had Se values around 99.4-109.1 μg/l, i.e., marginal Se saturation, whereas in the above mentioned experiment were included animals with sufficient initial Se status.…”

Section: Selenium Supplementation Experimentsmentioning

confidence: 99%

“…and for this reason they are added to feeds in various organic as well as inorganic forms (Pechova et al, 2008Krys et al 2009;Mala et al, 2009;Misurova et al, 2009a).…”

mentioning

confidence: 99%

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Impact of long-term supplementation of zinc and selenium on their content in blood and hair in goats

Pavlata¹,

Chomat²,

Pechová³

et al. 2011

Vet. Med. - Czech

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This paper evaluates the impact of long-term supplementation of different forms of zinc (Zn) and selenium (Se) on the content of these substances in the blood and hair of goats. Two analogous supplementation experiments were performed. 37 goats divided into four groups were used in the first trial with the Zn supplementation. Group A (n = 10) was a control group (with no Zn administered). A further three groups (B, C, D) were supplemented with Zn in various forms. Group B (n = 9) with zinc oxide, Group C (n = 9) with zinc lactate and Group D (n = 9) with zinc chelate. The second trial with Se supplementation was carried out on 20 goats divided into four groups. Group E (n = 5) was a control group. The other three groups were administered Se. Group F (n = 5) was supplied with a selenium lactate-protein complex, Group G (n = 5) with sodium selenite and Group H (n = 5) with selenium yeast. Three months later blood and hair samples were taken from all animals and Zn and Se concentrations were determined in whole blood, plasma, and hair. Glutathione peroxidase (GSH-Px) activity was determined in the Se supplementation trial group. At the end of the trial the Zn concentrations in plasma and whole blood were without major differences between the groups. The plasma concentration of Zn did not increase from the initial value at the start of the trial. In hair the average concentration of Zn was 95.2-100.0 mg/kg in all groups. No conclusive relation was confirmed between the values of Zn in hair and its concentration in blood. The Se concentration in whole blood (µg/l) at the end of trial in supplemented groups (F -188.8 ± 24.6; G -197.2 ± 10.9; H -190.1 ± 26.3) was significantly higher (P < 0.01) than in the control group (E -103.1 ± 23.5). Similarly, the activity of GSH-Px (µkat/l) was significantly higher in all supplemented groups (F -872.3 ± 94.8; G -659.5 ± 176.4; H -839.8 ± 150.8) than in the control group (E -379.1 ± 63.5). Se content in hair (µg/kg) was higher also in all trial groups (F -242.3 ± 41.5; G -200.5 ± 46.9; H -270.0 ± 106.8) than in the control group (E -174.7 ± 38.0). However, it was significantly (P < 0.05) higher only in Group F. A conclusive correlation was identified between the Se concentration in whole blood and its content in hair (r = 0.54; P < 0.05; n = 20). Based on the results it can be concluded that none of the supplemented forms of Zn increased its concentration in blood, plasma and hair. On the other hand, the administration of Se led to an increase in the Se concentration in blood, increased the activity of GSH-Px in whole blood and the Se content in hair. Based on the proven correlation and regression relation between the Se concentration in blood and its content in hair, hair can be considered as a suitable material for the diagnosis of long-term Se status in goats. Goats with sufficient Se status are those that have more than 160 µg/kg of Se in hair dry weight.

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Section: Selenium Supplementation Experimentssupporting

confidence: 78%

Section: Selenium Supplementation Experimentsmentioning

confidence: 99%

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Impact of long-term supplementation of zinc and selenium on their content in blood and hair in goats

Pavlata¹,

Chomat²,

Pechová³

et al. 2011

Vet. Med. - Czech

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“…There is comparatively little data in the literature on the selenium lactate-protein complex used in the present study. Pechova et al (2008) monitored selenium concentration in milk after peroral supplementation of goats with Se-enriched yeast, selenium lactate-protein complex and selenium proteinate. They observed significantly higher selenium levels in milk of goats supplemented with Se-enriched yeast as compared with the control group, lactate-protein complex and selenium proteinate group.…”

Section: Discussionmentioning

confidence: 99%

“…Studies on Se in goats are quite rare. Various Se forms in goat's milk were studied by Aspila (1991) and Pechova et al (2008). Studies on health problems caused by selenium deficiency or a combined selenium and vitamin E deficiency in goats (Tontis, 1984; Bickhardt et al, 1999; Culjak et al, 1999; Ramirez-Bribiesca et al, 2001) resulted in efforts to understand the effect of Se supplementation on increased Se levels in blood and its impact on animal health (Hayashida et al, 2003; RamirezBribiesca et al, 2005; Sanchez et al, 2007.…”

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confidence: 99%

Effect of a long-term peroral supplementation with sodium selenite and selenium lactate-protein complex on selenium status in goats and their kids

Mišurová¹,

Pavlata²,

Pechová³

et al. 2009

Vet. Med.

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AbstrAct:The aim of this study was to evaluate the effect of a long-term peroral selenium supplementation in the form of sodium selenite and selenium lactate-protein complex by comparing selenium concentrations and glutathione peroxidase activity in blood of goats and their kids as well as comparing selenium concentrations in goat colostrums. For the study, a total of 27 clinically healthy pregnant white shorthair goats were used. They were divided to three groups, i.e., the control group (C) without any selenium supplementation, sodium selenite group (E1) and selenium lactate-protein complex group (E2). For four months, experimental goats received 0.43 mg of selenium per animal per day in diet; goats from the control group were given 0.15 mg of selenium per animal per day. At the beginning of the experiment, goats of all groups showed an average selenium concentration of 96 μg/l in whole blood. On the parturition day, samples of first colostrum from goats and heparinized blood from goats and kids were taken. In the control group (C), average blood selenium concentrations of 111.4 ± 33.5 μg/l were observed on the parturition day. In both experimental groups, selenium concentrations were significantly higher (P < 0.05). Average selenium concentration in the sodium selenite group (E1) was 177.2 ± 34.8 μg/l and in the group supplemented with selenium lactate-protein complex (E2) 159.0 ± 28.5 μg/l. Average glutathione peroxidase (GSH-Px) activity in blood of control goats (C) was 581.9 ± 99.2 μkat/l, in group E1 1 154.6 ± 156.2 μkat/l and in group E2 1 011.6 ± 153.6 μkat/l. GSHPx activity in experimental groups was significantly higher (P < 0.05) as compared with the control group. Average selenium concentrations in colostrum was in the control group 40.1 ± 12.8 μg/l, in E1 99.0 ± 29.9 μg/l and in group E2 79.0 ± 17.7 μg/l. Colostral selenium concentrations in experimental groups were significantly higher (P < 0.05) as compared with the control group. No significant difference in the monitored parameters was found between experimental groups. In kids of control mothers (kC), average selenium concentrations in blood on the parturition day were 62.4 ± 22.9 μg/l; kids of mothers supplemented with sodium selenite (kE1) showed average selenium levels of 100.0 ± 31.2 μg/l, and the average selenium concentration in kids of mothers receiving lactate-protein complex was 83.4 ± 20.1 μg/l (kE2). Average GSH-Px activity in control kids (kC) was 402.1 ± 153.9 μkat/l. Kids from kE1 showed average activity of GSH-Px 806.1 ± 254.9 μkat/l and kids from group kE2 529.9 ± 119.8 μkat/l. Statistically significant difference (P < 0.05) was found only between kC and kE1 which showed significantly higher selenium concentration and GSH-Px activity. The results of this study confirm that both forms of selenium administered in experimental groups (i.e., sodium selenite and selenium lactate-protein complex) had similar biological effect in goats. However, results obtained in kids indicate a better effect of supplementation with sodium selenite.

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The Influence of Supplementation of Different Forms of Zinc in Goats on the Zinc Concentration in Blood Plasma and Milk

Pechová

Mišurová

Pavlata

et al. 2009

Biol Trace Elem Res

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The aim of the experiment was to study zinc concentration in goat's milk during a short-term oral supplementation of three organic and one inorganic form of zinc and the influence of Zn supplementation on the concentration of Zn and Cu in blood plasma. The experiment involved 31 lactating goats. The group C was the control, group L received zinc lactate, group A received zinc chelate, group T received amino acid-polypeptidic complex with zinc, and group O received zinc oxide. Zinc preparations were administered orally in 500 mg Zn per animal for 28 days. In the course of the experiment, Zn concentration in plasma increased significantly in all experimental groups and in the control group was unchanged. The concentration of zinc in milk during the experiment fluctuated in individual groups, but there were no significant differences between groups. After 28 days of Zn supplementation, Zn concentration in milk of goats was similar as at the start of the experiment in all groups. According to our results, the supplementation of different forms of zinc did not influence the concentration of Zn in milk, but significantly influenced the Zn concentration in blood plasma. The efficiency of different organic and inorganic forms of zinc was similar.

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Monitoring of Changes in Selenium Concentration in Goat Milk During Short-Term Supplementation of Various Forms of Selenium

Cited by 30 publications

References 24 publications

Impact of long-term supplementation of zinc and selenium on their content in blood and hair in goats

Impact of long-term supplementation of zinc and selenium on their content in blood and hair in goats

Effect of a long-term peroral supplementation with sodium selenite and selenium lactate-protein complex on selenium status in goats and their kids

The Influence of Supplementation of Different Forms of Zinc in Goats on the Zinc Concentration in Blood Plasma and Milk

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