Effect of a long-term peroral supplementation with sodium selenite and selenium lactate-protein complex on selenium status in goats and their kids

Mišurová, Ľ.; Pavlata, L.; Pechová, Alena; Dvořák, R.

doi:10.17221/107/2009-vetmed

Cited by 14 publications

(8 citation statements)

References 41 publications

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“…The similar effect of inorganic and organic selenium was observed also by Misurova et al (2009) in goats. Monterrosa et al (2011), who compared the effect of supplementation of selenium products on the digestive function of lambs, did not find any differences in selenium absorption and digestibility between animals receiving sodium selenite or selenomethionine.…”

Section: Blood Parameterssupporting

confidence: 81%

Effect of supplementation of various selenium forms and doses on selected parameters of ruminal fluid and blood in sheep

Panev¹,

Hauptmanová²,

Pavlata³

et al. 2013

Czech J. Anim. Sci.

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Effect of various doses and forms of selenium (organically bound vs. inorganic) on selected parameters of ruminal fluid and blood in sheep was evaluated. The trial was performed with 15 sheep divided into two groups. Animals from group A (n = 8) received a feeding mixture with selenomethionine, while sheep from group B (n = 7) were fed a mixture with sodium selenite. During the first 14 days, animals from both groups were fed a mixture with optimum dose of selenium (1 mg Se/kg dry matter). For another 28 days, all experimental animals received a Se-deficient mixture (0.1 mg Se/kg dry matter), whereas in the last 21 days of the experiment, animals were fed a high-Se diet (5.0 mg Se/kg dry matter). Throughout the trial, 4 samples of blood and ruminal fluid were taken from each animal. The samples of ruminal fluid were analyzed to determine the concentration of Se and identify other parameters of ruminal fermentations. Selenium levels were also determined in ruminal biomass. In blood, Se concentration, glutathione peroxidase (GSH-Px) activity, and other selected biochemical parameters were measured. The results of the present study demonstrate that the actual intake of both organic and inorganic Se is reflected in Se concentration in ruminal fluid and ruminal biomass and, similarly, in Se content and GSH-Px activity in blood. The form of supplemented selenium did not have a significant effect on ruminal fermentation parameters in dependence on different doses of Se contained in feeding rations (except for the negative effect of a sudden start of feeding high levels of organically bound Se on infusoria count, which was accompanied by the increase of GMT, LDH, and AST enzymes activity in ruminal fluid). The results also suggest possible negative interaction between the intake of organically bound selenium and the concentration of copper in blood of sheep.

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Section: Blood Parameterssupporting

confidence: 81%

Effect of supplementation of various selenium forms and doses on selected parameters of ruminal fluid and blood in sheep

Panev¹,

Hauptmanová²,

Pavlata³

et al. 2013

Czech J. Anim. Sci.

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“…For example, it was found that with different forms of selenium supplementation the speed or growth of activity can differ. Misurova et al (2009b) reported that sodium selenite and selenium lactateprotein complexs significantly increased Se levels in the whole blood and colostrum of adult goats as compared with the control group. In newborn kids, however, a significant increase in blood Se levels and GSH-Px activity was observed only in the kids of mothers supplemented with sodium selenite.…”

Section: Discussionmentioning

confidence: 96%

Direct and indirect assessment of selenium status in sheep - a comparison

Pavlata¹,

Mišurová²,

Pechová³

et al. 2012

Vet. Med. - Czech

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ABSTRACT:The aim of this study was to determine the relationship between selenium concentration and activity of glutathione peroxidase (GSH-Px) in the whole blood of sheep and reference ranges for the activity of GSH-Px for evaluation of the selenium status of sheep in the Czech Republic. Selenium concentration and activity of glutathione peroxidase were determined in whole blood samples collected from 92 sheep in six herds. The GSH-Px activity in the samples was measured using the photometric method. Selenium in the sample was measured using the hydride technique atomic absorption spectrometry. Data on both parameters were processed using correlation and regression analysis in order to obtain reference values of GSH-Px for the indirect evaluation of the selenium status of sheep. The two variables showed a close and significant correlation (r = 0.95; P < 0.01). The regression line, defined by the equation y = 7.5857x -121.87 (linear) or y = -0.0167x 2 + 11.993x -355.57 (polynomial), allowed us to determine the GSH-Px activity of 637, resp. 677 μkat/l as equivalent to selenium concentration in whole blood of sheep 100 μg/l. Mean selenium concentration and mean GSH-Px activity found in whole blood samples were 123.42 ± 57.84 μg/l and 814.34 ± 463.64 μkat/l, respectively. In this study, a close dependence of GSH-Px activity on the selenium concentration in the blood of sheep was found. Activity values of GSH-Px were determined for use in the diagnosis of sufficient selenium status in sheep in the Czech Republic (GSH-Px activity greater than 600 μkat/l of whole blood).

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“…On the basis of our results we may conclude that all forms of selenium applied increased the level of selenium in the blood of mothers and in the blood of kids, but we did not discover significant differences between the individual forms of selenium. Other authors also came to the conclusion that both the inorganic and organic form of selenium increased the selenium concentrations in the blood of lambs (Boldižárová et al, 2005), dairy cows (Juniper et al, 2006), and goats (Misurova et al, 2009a) in contrast to the control group. Leeson et al (2008) compared selenite, Se-enriched yeast, and B-Traxim Se in broilers and discovered that plasma concentrations of selenium did not differ significantly when using various forms of selenium.…”

Section: Discussionmentioning

confidence: 98%

Comparison of organic and inorganic forms of selenium in the mother and kid relationship in goats

Pavlata¹,

Mišurová²,

Pechová³

et al. 2012

Czech J. Anim. Sci.

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During pregnancy and lactation the mother's demands for selenium increase because selenium is necessary for the foetus and the newborn kids (Smith and Picciano, 1986; Anan et al., 2009). A decrease in the concentration of selenium in the blood was confirmed during parturition and beginning of lactation . Selenium concentrations also decreased in the liver of pregnant animals as compared to the non-pregnant ones; it was discovered that selenium The goal of the experiment was to compare the effect of four different forms of selenium (Se) − sodium selenite (SS), lactate-protein selenium complex (SL), selenium enriched yeast (SY), and seleniumproteinate (SP) supplemented to pregnant goats on Se concentration and glutathione peroxidase (GSH-Px) activity in the blood of goats on the day of delivery and also on Se concentration and GSH-Px activity in the blood of newborn kids. The experiment involved 33 pregnant goats of White Short-haired breed. The supplementation started 6 weeks before the parturition. The goats were divided into 5 groups: control group C, not supplemented, and 4 trial groups (SL, SP, SS, SY), which received Se in the above stated forms by the means of supplemented pellets (300 g per animal per day) at a rate 900 μg Se/kg of dry matter. The average Se concentrations in the blood of the goats were 79.6 μg/l in group C, 152.6 μg/l in group SL, 167.1 μg/l in group SP, 144.9 μg/l in group SS, and 152.9 μg/l in group SY. Selenium concentrations in all 4 trial groups were significantly higher (P < 0.01) than in control group, however no significant difference was found between individual trial groups. Likewise, the activity of GSH-Px in goat blood increased significantly in all supplemented groups compared to the controls; however we did not discover any significant differences in activity of GSH-Px between the individual selenium-supplemented groups. The Se concentrations in the blood of kids were significantly (P < 0.01) higher in the selenium-supplemented groups (SL -94.9 μg/l, SP -87.5 μg/l, SS -87.6 μg/l, SY -92.5 μg/l) than in the control group (C -49.4 μg/l), but we did not discover any differences between the individual experimental groups. The activity of GSH-Px in the blood of the kids tended towards higher values in the supplemented groups than in the control group, but the values were significantly higher (P < 0.05) only in groups SY and SL. We have found significant correlation between GSH-Px activity and Se concentration in the blood of goats (r = 0.86) and newborn kids (r = 0.95). Likewise, there was significant correlation between Se concentration in the blood of goats and their kids (r = 0.74). We discovered that the kids are reaching physiologically only about 60% of Se status in whole blood in comparison with their mothers. Our results are suggesting that all the above forms of Se were similarly utilised and transferred into the foetus in the goats.

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Effect of a long-term peroral supplementation with sodium selenite and selenium lactate-protein complex on selenium status in goats and their kids

Cited by 14 publications

References 41 publications

Effect of supplementation of various selenium forms and doses on selected parameters of ruminal fluid and blood in sheep

Effect of supplementation of various selenium forms and doses on selected parameters of ruminal fluid and blood in sheep

Direct and indirect assessment of selenium status in sheep - a comparison

Comparison of organic and inorganic forms of selenium in the mother and kid relationship in goats

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