Monilial (Candida) Endocarditis Following Treatment With Antibiotics

Incidence of candida in hospital in-patients and the effects of antibiotic therapy.

“…On the other hand, in a large series of cases, Robinson (1954) found a negligible incidence of symptoms proved to be due to candida in patients being treated with antibiotics, ahd Younger et al (1959) to show a correlation between overgrowth of candida and adverse symptoms after short-term antibiotic therapy. Proliferation of candida in many patients did not cause significant morbidity in this trial, but in view of the morbidity and even mortality which candida can occasionally produce (Reynell et al, 1953 ;Caplan, 1955), it would seem wise to contain or reduce the reservoir of candida when using antibiotics in certain patients.…”

Induction of Sarcoma in the Rat by Iron--Dextran Complex

“…Here, however, infection from the alimentary tract may have occurred at operation, since local peritoneal exudate infected with C. tropicalis was present between the stomach and liver at necropsy. Systemic candidiasis has been reported after duodenal perforation or abdominal operations on a number of occasions (Brown et al;Schaberg et al;Caplan, 1955;Matthias and Rees;Barrett et al).This case illustrates the various clinical factors predisposing to the development of systemic candidiasis. The history suggests that Candida may proliferate in the blood of a patient without any clinical signs of systemic moniliasis appearing other than pyrexia.…”

Treatment of trigeminal neuralgia with carbamazepine: a follow-up study.

“…Proliferation of candida in many patients did not cause significant morbidity in this trial, but in view of the morbidity and even mortality which candida can occasionally produce (Reynell et al, 1953 ;Caplan, 1955), it would seem wise to contain or reduce the reservoir of candida when using antibiotics in certain patients.…”