Incidence of candida in hospital in-patients and the effects of antibiotic therapy.

Comparison of Side-effects of Tetracycline and Tetracycline Plus Nystatin

“…Age and Candida.-The results in this trial agree with those of Stone and Mersheimer (1955-6), Childs (1956), and Smits et al (1966) in showing no association between age and isolation of Candida from faeces. They contrast, therefore, with the demonstration by Smits et al (1966) Candida and Symptoms.-In most trials of tetracycline and Mysteclin no valid measure of the association between symptoms and the presence of candida in the faeces has been possible, because either the candida isolations have been too few (Foltz et al, 1955-6;Hewitt et al, 1955-6;Younger et al, 1959), or the symptoms too few (Metzger et al, 1957), or both (Childs, 1956Tewari and Fletcher, 1966).…”

“…They contrast, therefore, with the demonstration by Smits et al (1966) Candida and Symptoms.-In most trials of tetracycline and Mysteclin no valid measure of the association between symptoms and the presence of candida in the faeces has been possible, because either the candida isolations have been too few (Foltz et al, 1955-6;Hewitt et al, 1955-6;Younger et al, 1959), or the symptoms too few (Metzger et al, 1957), or both (Childs, 1956Tewari and Fletcher, 1966). Smits et al (1966) assessed symptoms by questioning on admission and on the 6th and 12th days, but failed to find any relation between symptoms and the presence of Candida in mouth or rectal swabs.…”

Yeasts in a hospital for patients with skin diseases

“…Skin carriage of the yeasts, especially C. albicans, did not merely reflect contamination from the mouth and was highest in the group of patients with psoriasis. The incidence of all yeasts, not only C. albicans, is increased in the group of patients treated with antibiotics (Smits, Prior & Arblaster, 1966). As expected, systemic antibiotics produced a larger increase than did topical antibiotics, but increased incidence even in the gums did occur in those patients treated with topical antibiotics.…”

Factors influencing oral carriage of yeasts among individuals with diabetes mellitus

“…The effects of age are not always easily separated from disease and medical treatment [21,22]. Age was not related to isolation of yeasts from diabetics [2,3,17].…”