Mongolian Gerbil Tympanic Membrane: Normal and With Induced Otitis Media

Fulghum, Robert S.; Chole, Richard A.; Brinn, Jack E.; Branigan, Alan E.

doi:10.1001/archotol.1987.01860050067017

Cited by 12 publications

(3 citation statements)

References 10 publications

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“…Bacteria have been demonstrated in gerbilline OM and cholesteatoma [12][13][14] and were always present in the cholesteatoma matrix of our animals. By-products of trapped bacteria may factor into hyperproliferation of keratinocytes as significant thickening of canal epithelium did not occur until after occlusion.…”

Section: Discussionsupporting

confidence: 53%

Gerbilline Cholesteatoma Development. Part II: Temporal Histopathologic Changes in the Tympanic Membrane and Middle Ear

Tinling

Chole

2006

Otolaryngol.--head neck surg.

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Section: Discussionsupporting

confidence: 53%

Gerbilline Cholesteatoma Development. Part II: Temporal Histopathologic Changes in the Tympanic Membrane and Middle Ear

Tinling

Chole

2006

Otolaryngol.--head neck surg.

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“…However, in these studies, middle ear infections were induced by the injection of suspensions of various exogenous bacterial strains into the middle ear cavity. 7–10 The infections induced in this way were usually low grade and recovered spontaneously within a short period. The structure of the lamina propria of the tympanic membrane was reported to be little affected.…”

Section: Introductionmentioning

confidence: 99%

Middle Ear Effusions and Structure of the Tympanic Membrane

Wielinga

Peters²,

Tonnaer³

et al. 2001

The Laryngoscope

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“…The Mongolian gerbil, Meriones ungiuiculatus, has been used considerably as a laboratory animal (1,18,19,24) and as an animal model of disease (2,(4)(5)(6)(7)(8)14). It is also popular as a pet and is widely available to the public in pet stores.…”

mentioning

confidence: 99%

Cecal and fecal bacterial flora of the Mongolian gerbil and the chinchilla

Worthington

Fulghum

1988

Appl Environ Microbiol

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The Mongolian gerbil is being increasingly used as a laboratory animal and as a pet. Both chinchillas and gerbils are used as animal models for otitis media and other otic research. Previously, only incomplete information was available regarding the indigenous bacterial flora of the lower intestinal tracts of these coprophagic animals. Using the strict anaerobic methodology of the Virginia Polytechnic Institute Anaerobe Laboratory, we studied the predominant bacterial flora of the cecum and fecal pellets of the gerbil and the chinchilla and the bacterial flora of digesta pellets in the proximal colon. We found species of the following anaerobic genera in high dilutions of gerbil fecal pellets: Bifidobacterium, Clostridium, Propionibacterium, Lactobacillus, and Bacteroides. Only lactobacilli were found in high dilutions of digesta from the upper colon, although the cecum yielded Peptostreptococcus, Bifidobacterium, Clostridium, Lactobacillus, Propionibacterium, and Bacteroides species from high dilutions of cecal contents. The facultatively anaerobic and aerobic flora isolated consisted of species of Bacillus, Streptococcus, Staphylococcus, Acinetobacter, Alcaligenes, Escherichia, Pasteurella, and Pseudomonas plus several unidentifiable organisms. Species of Bifidobacterium, Bacteroides, Eubacterium, and anaerobic Lactobacillus were isolated from chinchillas.

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Mongolian Gerbil Tympanic Membrane: Normal and With Induced Otitis Media

Cited by 12 publications

References 10 publications

Gerbilline Cholesteatoma Development. Part II: Temporal Histopathologic Changes in the Tympanic Membrane and Middle Ear

Gerbilline Cholesteatoma Development. Part II: Temporal Histopathologic Changes in the Tympanic Membrane and Middle Ear

Middle Ear Effusions and Structure of the Tympanic Membrane

Cecal and fecal bacterial flora of the Mongolian gerbil and the chinchilla

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