Molluscicidal activity of some marine substances against the snail Biomphalaria glabrata (Mollusca, Planorbidae)

Miyasato, Patrícia A.; Kawano, Toshie; Freitas, José Carlos de; Berlinck, Roberto G. S.; Nakano, Eliana; Tallarico, L. F.

doi:10.1007/s00436-011-2712-x

Cited by 29 publications

(13 citation statements)

References 38 publications

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“…control by molluscicides is one of the main strategies to reduce the snail population in infected areas, there are few effective molluscicides commercially available. Therefore, natural products may be considered as potentially useful and safe molluscicides (Miyasato et al 2012). In this research, the compound 8, in comparison with the main components of the ethanolic extract of J. elliptica by Santos and Sant’Ana (1999), showed an activity (LC 90 = 36.43 μg/mL) lower than that of jatrophone (LC 90 = 8.91 μg/mL) but much higher than those of the jatropholones A and B (LC 90 = 206.16 μg/mL).…”

Section: Discussionmentioning

confidence: 99%

A penta-substituted pyridine alkaloid from the rhizome of Jatropha elliptica (Pohl) Muell. Arg. is active against Schistosoma mansoni and Biomphalaria glabrata

et al. 2014

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Jatropha elliptica is a shrub distributed throughout the north and west of Brazil and reputedly possesses a wide range of therapeutical properties. The roots of this plant possess molluscicidal activity and contain terpenoids, coumarin, lignoid, steroids and alkaloid. In the present study, we assessed the schistosomicidal, miracicidal and cercaricidal activities (against Schistosoma mansoni) and molluscicidal activities (against adults and egg masses of Biomphalaria glabrata) of the alkaloid diethyl 4-phenyl-2,6-dimethyl-3,5-pyridinedicarboxylate, isolated from the ethanol extract of the rhizome of J. elliptica, have been determined. The alkaloid was 100 % lethal to adult schistosomes within 4 days at a concentration of 50 μg/mL. Alterations were observed in the schistosome tegument occasioned by treatment with the alkaloid, such as formation of vesicles and vacuolisation. The extent of tegumental damage of the worm was proportional to the time of incubation and to the concentration of compound. The alkaloid also exhibited a potent cercaricidal activity (LC100 = 2 μg/mL); it was totally ineffective against miracicidal forms of the parasite. Moreover, the alkaloid presented strong activity against adult snails (LC90 = 36.43 μg/mL) but was inactive against their egg masses. It is observed then the potential of this compound for the development of new therapies for the treatment of schistosomiasis.

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Section: Discussionmentioning

confidence: 99%

A penta-substituted pyridine alkaloid from the rhizome of Jatropha elliptica (Pohl) Muell. Arg. is active against Schistosoma mansoni and Biomphalaria glabrata

et al. 2014

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“…Studies with molluscicides compounds show that it is usual to obtain the death of B. glabrata snail but not the embryos 18 23 25 . The lack of ovicidal activity allows the permanence of the snail host in the environment, maintaining the transmission of schistosomiasis.…”

Section: Resultsmentioning

confidence: 99%

“…However, niclosamide, has plenty of adverse factors, such as, non-selective toxicity, that harms other aquatic organisms; high cost; instability in sunlight, which in addition requires frequent reapplication due to the permanence of surviving snails after its application 1 10 32 . Thus, novel natural molluscicidal should be investigated as a possible alternative to synthetic products 16 17 18 25 .…”

Section: Introductionmentioning

confidence: 99%

OVICIDAL EFFECT OF PIPERACEAE SPECIES ON Biomphalaria glabrata, Schistosoma mansoni HOST

Rapado

Lopes

Yamaguchi

et al. 2013

Rev. Inst. Med. trop. S. Paulo

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SUMMARYSchistosomiasis is a neglected disease with public health importance in tropical and subtropical regions. An alternative to the disease control is the use of molluscicides to eliminate or reduce the intermediate host snail population causing a reduction of transmission in endemic regions. In this study nine extracts from eight Piperaceae species were evaluated against Biomphalaria glabrata embryos at blastula stage. The extracts were evaluated in concentrations ranging from 100 to 10 mg/L. Piper crassinervium and Piper tuberculatum extracts were the most active (100% of mortality at 20 mg/L and 30 mg/L respectively).

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“…A series of exploratory experiments were conducted using different concentrations to determine the toxicity range of the algal extracts against the tested snails. In the current experiment, five concentrations of aqueous and ethanol extract, each (100, 200, 300, 400 and 500 ppm) for each algal species were used for snails (Miyasato et al 2012). Ten snails were transferred to a glass aquarium containing 50 ml dechlorinated tap water as control and three replicates each of ten snails were used for each mentioned algal concentration.…”

Section: Preliminary Experiments For Determination Of Molluscicidal Tomentioning

confidence: 99%

Molluscicidal effect of some red and green marine algae on Lymnaea natalensis

Saad¹,

Hassanain²,

Darwish³

et al. 2019

Egypt. J. of Aquatic Biolo. and Fish.

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Molluscicide Fasciola gigantica bioactive metabolites Ulva lactuca Jania rubens Marine algae are economically important aquatic photosynthetic organisms act as a source of highly bioactive metabolites that might be useful against predators and parasites. In the present study, aqueous and ethanol extracts of four algal species of marine algae; Pterocladia capillacaea (P. capillacaea), Jania rubens (J. rubens), Ulva lactuca (U. lactuca), and Enteromorpha intestinalis (E. intestinalis) were tested for their lethal effect on Lymnaea natalensis (L. natalensis) snail, the intermediate host of the trematode parasite; Fasciola gigantica, (F. gigantica). Preliminary experiments were done to determine the molluscicidal toxicity of different concentrations of aqueous and ethanol algal extracts against the studied snail. Five concentrations of aqueous and ethanol extracts; 100, 200, 300, 400 and 500 ppm for each algal species were used. LC 50 for each extract was calculated daily till the end of the experiment. It is clear from the results that molluscicidal effect of algal extracts is concentration dependent. The most potent extracts as proved by calculated LC 50 are P. capillacaea and J. rubens aqueous extract (red algae); 111.3 and 127 ppm respectively and U. lactuca ethanolic extract (green algae) 121 ppm. The current study introduces marine algae of promising molluscicidal activity on L. natalensis snail. P. capillacaea and J. rubens aqueous extracts and U. lactuca ethanolic extract are the most potent and highly significant ones in the net reproductive rate and reduction. Further investigations for isolation of active principals of the algal potent extracts for evaluation as molluscicides and or anthelmintics are necessary required.

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Molluscicidal activity of some marine substances against the snail Biomphalaria glabrata (Mollusca, Planorbidae)

Cited by 29 publications

References 38 publications

A penta-substituted pyridine alkaloid from the rhizome of Jatropha elliptica (Pohl) Muell. Arg. is active against Schistosoma mansoni and Biomphalaria glabrata

A penta-substituted pyridine alkaloid from the rhizome of Jatropha elliptica (Pohl) Muell. Arg. is active against Schistosoma mansoni and Biomphalaria glabrata

OVICIDAL EFFECT OF PIPERACEAE SPECIES ON Biomphalaria glabrata, Schistosoma mansoni HOST

Molluscicidal effect of some red and green marine algae on Lymnaea natalensis

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