Molecule-electron-proton transfer in enzyme-photo-coupled catalytic system

Enhancing the catalytic efficiency and stability of photoenzymes using hydrogen-bonded organic framework material HOF-101

“…It has been reported that the enhancement of cofactor-intermediate shuttling process may positively affect the overall efficiency of photoenzyme-catalyzed reactions. 22 In this study, it was found that the catalytic efficiency of TML@HOF-101 was significantly higher than that of TM@HOF-101 + free L, and this is most likely due to the enhanced shuttling process of NAD + /NADH (dynamic diameter: ∼ 1.7 nm, 23 Fig. 5c).…”

“…To the best of our knowledge, this study represents the first report of HOFs in the field of photoenzyme catalysis, demonstrating their significant potential for application. Drawing on Li's recent molecular theory, 22 ''Molecule-electronproton transfer in enzyme-photocoupled catalytic systems'', this work highlights several advantages of HOF-101 over ZIF-8. In terms of enhanced molecular transfer, HOF-101 possesses a larger specific surface area, thereby increasing the catalyst loading capacity.…”

Efficient NADH Regeneration without Electron Mediator toward Enzymatic CO2 Reduction Enabled by a Lawn-like TP-COFs/Ti3C2Tx (MXene) Photocatalyst

“…However, under both conditions, with or without [Cp*Rh(bpy)(H 2 O)] 2+ , the difference in activity for the CO 2 reduction reaction (Figure 5) is higher compared to that of NADH regeneration reaction (Figure 4). This may be attributed to the variations in the mass transfer efficiency of NADH to the FDH enzyme 80 and selectivity of 1,4-NADH (Figure S14) 81 in both scenarios.…”

Core–shell BaPP@BDO-Rh benzimidazole oligomer photocatalyst can effectively promote NADH regeneration and CO2 conversion to fumarate

“…[1][2][3] Photoenzyme catalysis represents a sustainable and environmentally friendly approach to biomanufacturing, as it combines the light-collecting ability of photocatalysts with the high selectivity of enzymes to convert clean and inexhaustible light energy into chemical energy. [4][5][6] Since 1961, the chloroplasts of spinach have been employed for photoenzyme catalysis, and subsequent studies have explored the use of photocatalysts like titanium dioxide and graphite-phase nitrogen carbide. 3,[7][8][9][10][11] However, the current efficiency of regenerating photocatalytic cofactors and converting light energy remains relatively low.…”