Molecular Signals and Genetic Regulations of Neurological Disorders

Villani, Emanuele Rocco; Marzetti, Emanuele

doi:10.3390/ijms24065902

IJMS

2023

DOI: 10.3390/ijms24065902

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Molecular Signals and Genetic Regulations of Neurological Disorders

Emanuele Rocco Villani

Emanuele Marzetti

Abstract: Neurological disorders are a large and heterogeneous field of research that can be tackled through a variety of approaches, ranging from epidemiology to molecular biology, through clinical, biostatistical, and laboratory experiments [...]

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2024

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Gold Nanoparticles in Neurological Diseases: A Review of Neuroprotection

Chiang,

Yang,

Nicol

et al. 2024

IJMS

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This review explores the diverse applications of gold nanoparticles (AuNPs) in neurological diseases, with a specific focus on Alzheimer’s disease (AD), Parkinson’s disease (PD), and stroke. The introduction highlights the pivotal role of neuroinflammation in these disorders and introduces the unique properties of AuNPs. The review’s core examines the mechanisms by which AuNPs exert neuroprotection and anti-neuro-inflammatory effects, elucidating various pathways through which they manifest these properties. The potential therapeutic applications of AuNPs in AD are discussed, shedding light on promising avenues for therapy. This review also explores the prospects of utilizing AuNPs in PD interventions, presenting a hopeful outlook for future treatments. Additionally, the review delves into the potential of AuNPs in providing neuroprotection after strokes, emphasizing their significance in mitigating cerebrovascular accidents’ aftermath. Experimental findings from cellular and animal models are consolidated to provide a comprehensive overview of AuNPs’ effectiveness, offering insights into their impact at both the cellular and in vivo levels. This review enhances our understanding of AuNPs’ applications in neurological diseases and lays the groundwork for innovative therapeutic strategies in neurology.

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Gold Nanoparticles in Neurological Diseases: A Review of Neuroprotection

Chiang,

Yang,

Nicol

et al. 2024

IJMS

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Molecular Signals and Genetic Regulations of Neurological Disorders

Abstract: Neurological disorders are a large and heterogeneous field of research that can be tackled through a variety of approaches, ranging from epidemiology to molecular biology, through clinical, biostatistical, and laboratory experiments [...]

Cited by 1 publication

References 9 publications

Gold Nanoparticles in Neurological Diseases: A Review of Neuroprotection

Gold Nanoparticles in Neurological Diseases: A Review of Neuroprotection

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