Abstract:Middle ear ailments include a broad range of pathological conditions. Otitis media is the leading middle ear disease of childhood, which incurs significant health care resources in developed countries and, in developing countries, causes significant mortality and morbidity. Recurrent and chronic infections of the middle ear lead to the prolonged presence of inflammatory factors and cellular infiltrates resulting in temporary hearing loss. However, long-term alteration of the middle ear space can pose the risk … Show more
The practice of non-invasive trans-tympanic delivery faces multi-dimensional challenges. Suitable formulation for administration, permeability of the tympanic membrane, pharmacokinetics in middle and inner ear should be considered in design.
The practice of non-invasive trans-tympanic delivery faces multi-dimensional challenges. Suitable formulation for administration, permeability of the tympanic membrane, pharmacokinetics in middle and inner ear should be considered in design.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.