Molecular recognition of carbohydrates by functionalized zinc porphyrins

Mizutani, Tadashi; Murakami, Takeshi; Matsumi, Noriyoshi; Kurahashi, Takuya; Ogoshi, Hisanobu

doi:10.1039/c39950001257

Cited by 23 publications

(14 citation statements)

References 13 publications

(2 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[3c] This motif was combined again with H-bonding sites in the ªU-shapedº receptors 49 ± 51, by Mizutani, Ogoshi et al With octyl b-d-glucoside (12) in CHCl 3 , these molecules were able to form complexes with K a 180, 2090, and 41 400 m À1 , respectively. [29] Receptor 50 (but not 51) once more increased in potency on addition of a small quantity of hydroxylic solvent.…”

Section: Valleys Bowls Rings and Cages: Further Architectures Withmentioning

confidence: 94%

Carbohydrate Recognition through Noncovalent Interactions: A Challenge for Biomimetic and Supramolecular Chemistry

Davis

Wareham

1999

Angew. Chem. Int. Ed.

478

View full text Add to dashboard Cite

Carbohydrates are not always as "sticky" as one might expect. Even in organic solvents they are difficult targets for the supramolecular chemist, due to their complex, three-dimensional structures. In their natural environment (water) they are especially elusive, presenting challenges which will occupy synthetic and theoretical chemists for some time to come. The complex of an octaamide supramolecular receptor with beta-D-glucopyranose, which binds through apolar and polar contacts, is shown.

show abstract

Section: Valleys Bowls Rings and Cages: Further Architectures Withmentioning

confidence: 94%

Carbohydrate Recognition through Noncovalent Interactions: A Challenge for Biomimetic and Supramolecular Chemistry

Davis

Wareham

1999

Angew. Chem. Int. Ed.

478

View full text Add to dashboard Cite

show abstract

“…Zinc porphyrins are known to bind to a variety of diols, including many saccharides, such as glucosides and mannosides (Bonar-Law and Sanders, 1995;Mizutani et al, 1995). Resorcinarenes have also been reported to be able to extract some sugars (Tanaka et al, 1989).…”

Section: ) Glucose/fructose Separationmentioning

confidence: 99%

Recent achievements in facilitated transport membranes for separation processes

Ferraz

Duarte

Luccio

et al. 2007

Braz. J. Chem. Eng.

View full text Add to dashboard Cite

-Membrane separation processes have been extensively used for some important industrial separations, substituting traditional methods. However, some applications require the development of new membranes. In this work, we discuss recent progress achieved in this field, focusing on gas and liquid separation using facilitated transport membranes. The advantages of using a carrier species either in a liquid membrane or fixed in a polymer matrix to enhance both the flux and the selectivity of the transport are summarized. The most probable transport mechanisms in these membranes are presented and the improvements needed to spread this technology are also discussed. As examples, we discuss our very successful experiences in air fractioning, olefin/paraffin separation and sugar recovery using liquid and fixed carrier membranes.

show abstract

“…For example, boronic acid porphyrins have been used for sugar sensing [96][97][98][99][100][101][102][103][104][105] , discrimination of sugars [106,107] , and have been used to control sugar-DNA interactions [108] . Boronic acid porphyrins have also been employed in glycosylated steroid sensing [109] and the detection of carbohydrates on the surface of cells using a photochemical approach [110] .…”

Section: Porphyrin Carbohydrate Interactionsmentioning

confidence: 99%

Chemical Synthesis and Medicinal Applications of Glycoporphyrins

Moylan¹,

Scanlan²,

Senge

2015

CMC

View full text Add to dashboard Cite

Abstract:This review presents an in-depth overview of the modification of porphyrins with bioconjugates and their applications in medicine today. Porphyrin bioconjugates ranging from nucleotides to steroids are under active scrutiny. However, carbohydrates have been at the forefront of such research in recent years and offer significant potential. This is attributed to their own selectivity to lectins on the surface of cancer cells and their influence on the amphiphilicity of the porphyrin macrocycle. These characteristics and the tendency of porphyrin photosensitizers to accumulate in tumor tissues make glycoporphyrins promising candidates for use as photosensitizers. Thus, a detailed overview of the synthesis and biological evaluation of glycoporphyrins is given with a particular focus on their applications in photodynamic therapy and their future prospects as drug candidates have been reported.

show abstract

Molecular recognition of carbohydrates by functionalized zinc porphyrins

Cited by 23 publications

References 13 publications

Carbohydrate Recognition through Noncovalent Interactions: A Challenge for Biomimetic and Supramolecular Chemistry

Carbohydrate Recognition through Noncovalent Interactions: A Challenge for Biomimetic and Supramolecular Chemistry

Recent achievements in facilitated transport membranes for separation processes

Chemical Synthesis and Medicinal Applications of Glycoporphyrins

Contact Info

Product

Resources

About