Molecular interactions of MnO₂@RGO (manganese dioxide-reduced graphene oxide) nanocomposites with bovine serum albumin

Application of non-metal nanoparticles, as a novel approach, for improving the stability of blood products: 2011–2021

“…Researchers suggested the usage of nanocomposites instead of individual nanoparticles for enhanced efficacy of them in biomedical applications. The effect of GO-based nanocomposites on BSA have been studied (Baral et al 2020 ; Naskar et al 2017 ). Naskar et al demonstrated the interaction of synthesized ZnO graphene nanocomposite with BSA and suggested the application of these nanocomposites for biomedicine (Naskar et al 2017 ).…”

“…BSA esterase-like activity was slightly affected after adsorption on NCs. Aggregates of various sizes were formed from the protein-NC complexes consisting of nanorod and sheet-like shapes (Baral et al 2020 ).…”

Facile preparation of covalently functionalized graphene with 2,4-dinitrophenylhydrazine and investigation of its characteristics

“…14 Therefore, GO sheets are strongly oxidized and characterized by oxygen-containing groups. 15,16 To remove these groups and prepare R-GO, various reducing agents; such as hydrazine, 17,18 strong alkaline environments, 19 vitamin C, 20,21 and bovine serum albumin (BSA); 22,23 and various methods; such as electrochemical, 24,25 photochemical, 26,27 and thermal reduction 28,29 procedures; have been used.…”

A Non-Immunized and BSA-Template Aggregation-Induced Emission Sensor for Noninvasive Detection of Cystatin C in the Clinical Diagnosis of Diabetes Nephropathy

“…25 Therefore, it has been urgent to establish a sensitive nonimmune method for simple detection of Cys C. In recent years, fluorescent probes have become a powerful tool for sensor and analytical imaging due to their high resolution and good biocompatibility. 26,27 Most of the fluorescent molecules are insoluble in water and the aggregation of fluorescent molecules in aqueous solution will lead to fluorescence quenching, namely, aggregation-caused quenching (ACQ). 28,29 Therefore, the fluorescent probes can only emit light in low-concentration aqueous solution and are easily disrupted by background signal or false positive signal, which affects their performance in special environment.…”

“…PETIA and PENIA have been the most widely used methods in clinical practice, but both of them require preparation of expensive antibodies, taking the obstacles to clinical application because of the high cost . Therefore, it has been urgent to establish a sensitive nonimmune method for simple detection of Cys C. In recent years, fluorescent probes have become a powerful tool for sensor and analytical imaging due to their high resolution and good biocompatibility. , Most of the fluorescent molecules are insoluble in water and the aggregation of fluorescent molecules in aqueous solution will lead to fluorescence quenching, namely, aggregation-caused quenching (ACQ). , Therefore, the fluorescent probes can only emit light in low-concentration aqueous solution and are easily disrupted by background signal or false positive signal, which affects their performance in special environment. In 2001, academician Tang et al discovered that the derivatives of silole did not emit light in dilute solution, but the fluorescence increased rapidly with the aggregation of molecules, , which was defined as aggregation-induced emission (AIE) .…”