Molecular imprinted polymers based on magnetic chitosan with different deep eutectic solvent monomers for the selective separation of catechins in black tea

Abstract

Two types of molecular-imprinted polymers-based magnetic chitosan with facile deep eutectic solvent-functional monomers (Fe O -CTS@DES-MIPs) were synthesized and applied as adsorbents in magnetic solid-phase extraction (MSPE) for the selective recognition and separation of (+)-catechin, (-)-epicatechin, and (-)-epigallocatechin gallate in black tea. The obtained Fe O -CTS@DES-MIPs were characterized by Fourier transform infrared spectroscopy and field emission scanning electron microscopy. The selective recognition ability was examined by adsorption experiments. The actual amounts of (+)-catechin, (-)-epicatechin, and (-)-epigallocatechin gallate extracted from black tea using Fe O -CTS@DES-MIPs by the MSPE method were 13.10, 6.32, and 8.76 mg/g, respectively. In addition, the magnetic Fe O -CTS@DES-MIPs showed outstanding recognition and selectivity. Therefore, it can be used to separate bioactive compounds from black tea. The new-type of DES adopted as the functional monomer in this paper provides a new perspective for the recognition and separation of bioactive compounds.

Polymer Science and Engineering Using Deep Eutectic Solvents

“…One of the most recent applications of DES is its use for the production of MIPs, either as medium or solvent [50,51], as MIPs modifier [51,52,53,54,55,56,57,58,59,60,61,62,63], as MIPs functional monomer [48,53,54,64,65,66,67,68,69,70,71,72], and even as MIPs template [67,69] (Table 2). From the whole publications involving DES and polymers, more than 15% correspond to DES and MIPs, reported just in the last four years [18].…”

Involvement of Deep Eutectic Solvents in Extraction by Molecularly Imprinted Polymers—A Minireview

“…While there are a number of examples that meet point 1 (see Table 1), data to meet points 2 and 3 are very rare. In MIPs preparation methodologies, the DESs can be applied as medium or porogen, functional monomer [32][33][34], MIPs modifier [35,36], or MIPs The monomers are selected according to their ability to interact with the functional groups of the template molecule. After polymerization, the template molecules are extracted/removed from the polymeric matrix and binding sites, having their shape, size, and functionalities complementary to the target molecule established.…”

“…While there are a number of examples that meet point 1 (see Table 1), data to meet points 2 and 3 are very rare. In MIPs preparation methodologies, the DESs can be applied as medium or porogen, functional monomer [32][33][34], MIPs modifier [35,36], or MIPs template [33,37]. Such systems will be abbreviated as DES-MIPs.…”

Solid-Phase Extraction of Catechins from Green Tea with Deep Eutectic Solvent Immobilized Magnetic Molybdenum Disulfide Molecularly Imprinted Polymer

“…(+)-Catechin (C), (−)-epicatechin (EC), (−)-epigallocatechin (EGC), (−)-epicatechin gallate (ECG), and (−)-epigallocatechin gallate (EGCG) are the main catechins in green tea. Their excellent anti-oxidation, anti-cancer, and anti-cancer activities have prompted research into the separation and purification of those bioactive compounds [7][8][9]. The separation and purification technologies include distillation, freezing clarification, organic solvent extraction, and ion exchange.…”