Molecular identification of TEM-116 beta-lactamase gene in isolates of pathogenic <i>Pseudomonas aeruginosa</i>: A first report from Pakistan

TEM Gene Detection in Clinical Pseudomonas aeruginosa and Escherichia coli Samples

“…Pseudomonas aeruginosa is a major cause of infections, such as pneumonia, bacteremia, urinary tract infections, as well as cystic fibrosis, in hospitals with weak safety systems (1). Escherichia coli is the most common cause of urinary tract infections (2).…”

Prevalence of antibiotic resistance and virulent factors in nosocomial clinical isolates of Pseudomonas aeruginosa from Panamá

“…Pyoverdine pigment production is ubiquitous amongst β-lactamase-producing strains of P. aeruginos a. Because both pyoverdine and β-lactamase production are necessary for the acquisition of drug resistance capabilities, 25 , 26 we decided to screen our isolates for the presence of ESBLs genes such as blaTEM, blaCTX-M and blaSHV using PCR. Twenty-two strains were PCR positive for the presence of the ESBL blaTEM1-like genes (43%) ( Fig.…”

“… 23 Therefore, the characterization of β-lactamases from drug-resistant P. aeruginosa can greatly contribute to the understanding of mechanisms of molecular pathogenesis, antibiotic resistance and virulence in bacteria<-- -->. 25 , 26 …”

Resistencia enzimática en Pseudomonas aeruginosa, aspectos clínicos y de laboratorio

“…Las EMA inactivan los aminoglucósidos mediante la unión de grupos acetilo, fosfato o adenilo a los sustituyentes amino e hidroxilo en la molécula del antimicrobiano (Tabla 4). Estas modificaciones reducen significativamente la afinidad de los aminoglucósidos por la diana (subunidad ribosomal 30S) y bloquean su actividad 21 .…”