Molecular Genetic Testing of Osteoporosis Susceptibility in Postmenopausal Women in Moscow

Association of vitamin D receptor gene with anthropometric measures in Komi ethnic group

“…It means that body weight increases relatively to the height due to the muscle and fat tissues but not to the bone tissues in FF genotype carriers; while Ff genotype carriers demonstrated the higher impact of skeleton weight compared to other compo nents of body composition. We do not assume the observed decrease in the bone mass content in FF carriers contradictory to the reported increased resorption rates of bone mass in Russians and French women with the ff FokI geno type compared to the FF genotype (Myakotkin et al, 2011;Eccleshall et al, 1998). The mentioned studies were performed in older women, while young individuals in the period of rapid growth followed by stabilization of body size were studied in the present study.…”

“…The studied sample differed insignificantly in FokI and BsmI allele frequencies from the Russians from Moscow (Myakotkin et al, 2011;Taghieva et al, 2005). It might be concluded that the distribution of the VDR gene alleles in the Komi (zyryan) sample is similar to the Caucasians' variability spectrum.…”