Molecular genetic markers of economically important traits in dairy cattle

Yudin, N. A.; Воевода, М. И.

doi:10.1134/s1022795415050087

Cited by 27 publications

(15 citation statements)

References 80 publications

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“…Now, according to the OMIA database (www.omia.org; Lenffer et al, 2006), 272 bovine traits are known to be genetically controlled, including a number of diseases. For 175 of them, causative mutations in the coding and non-coding regions of DNA have already been identified, the effect of which is related to various mechanisms, including changes in the protein sequence, in the stability, expression or processing of RNA (Ibeagha-Awemu et al, 2008;Yudin, Voevoda, 2015;Ciepłoch et al, 2017). Using this information, tests were developed for genotyping pathological mutations and removing carrier animals from the breeding herd (Romanenkova et al, 2015;Fornara et al, 2019;Sabetova et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of allele frequencies for DNA polymorphisms associated with disease and economically important traits in the genomes of Russian and foreign cattle breeds

et al. 2022

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The genetic makeup of a breed including its genetic differences from other breeds determines its appearance and characteristics, including economically important traits and resistance to pathologies. To date, many loci controlling significant phenotypes have been identified, which is successfully used in the world practice of marker-assisted selection to improve breed properties. The aim of this study was a comparative analysis of frequencies for known causative nucleotide substitutions, insertions and deletions associated with disease and economically important traits in Russian and foreign cattle breeds. As a result, we identified frequencies of these DNA polymorphisms in the populations of Russian cattle breeds, compared them with those of foreign populations of the same breed, as well as other foreign breeds. Our results indicate similarities in frequencies for most of such alleles within breeds (populations of Russian and foreign breeding), as well as the relationship between the causative allele prevalence and the presence of phenotypic traits under the effect. We also found an excess of some undesirable alleles in the Russian cattle populations, which should be paid attention to when designing breeding programs. We found that the alleles increasing fertility in the Hereford breed have a higher frequency in the Russian Hereford population compared to the foreign counterpart. Interestingly, unlike for the European breeds, for Asian Turano-Mongolian Wagyu and Yakut cattle, there was a less clear link between phenotypic traits and frequencies of known causative alleles. Our work points to specific genetic variants that could be used to improve and/or maintain the performance of certain cattle breeds bred in the Russian Federation.

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Section: Introductionmentioning

confidence: 99%

Comparative analysis of allele frequencies for DNA polymorphisms associated with disease and economically important traits in the genomes of Russian and foreign cattle breeds

et al. 2022

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“…Previous studies have provided abundant evidence on different ways to increase the productive life of livestock by varied animal maintenance and breeding methods [4][5][6]. It has been established the impact of the first calving time, the milk yield for the first lactation, the calving season, linear affiliation, pedigree, servicing bulls and other factors on the lifespan [7,8].…”

Section: Introductionmentioning

confidence: 99%

The effect of holstein bulls’kappa-casein gene genotype on the productive longevity of their female offspring in the republic of Bashkortostan

et al. 2021

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Increased productivity in the industry can be achieved by breeding for productive longevity through searching and using genetic markers. The study analysed the data of 1476 animals with at least one completed lactation. Depending on the linear affiliation and kappa-casein gene genotype of servicing bulls, their female offspring were divided into 4 groups. The CSN3 A allele frequency in the studied bulls was 81.91%, the CSN3 B allele was 18.09%. The highest frequency of the desired CSN3 B allele in the servicing bulls-producers of the Reflection Sovering line was 20.83%, which is 3.69% more than in the bulls of the Vis Back Ideal line. The animal life length analysis showed that the female progeny of bulls from the Reflection Sovering line (2.46 lactation), especially those with the CSN3 AB genotype (2.59 lactation), had the longest life. The offspring of CSN3AB genotype bulls of the Reflection Sovering line had the highest lifetime milk yield (18490 kg). The CSN3AB genotype cows of the Reflection Sovering line had the highest average milk yield on the 1st day of a cow’s life of 9.05 kg.

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“…At present, molecular genetics acts as the most diverse approaches and methods to be applied in animal husbandry, including testing breeding animals, their selection that depends on the genetic variants of productivity, diagnosis of hereditary diseases, research on the diversity and genetic structure of a herd, editing the genome and more [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Evaluation towards stud bulls with different mixed genotypes relating to somatotropin cascade genes by origin

Zagidullin¹,

Gilemhanov²,

Хисамов³

et al. 2020

BIO Web Conf.

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A preliminary evaluation towards a breeding value of the Holstein breeding bulls with different genotypes of somatotropin cascade genes is presented: pituitary transcription factor or growth hormone factor (PIT1), prolactin (PRL), somatotropin (GH), somatotropin releasing hormone (GHRH), insulin-like (IGF-1) in the conditions of the Republic of Tatarstan. The research studies the signs (indices) of milk productivity (milk yield and fat in milk) of the closest female ancestors of bulls with different genotypes of somatotropin cascade genes. Studies and analysis have shown that the bulls with the mixed genotypes ABAALLBBAA (10269 kg), AAAALLBBAB (4.13 %) and BBAALLABBB (9402 kg and 4.06 %) had the highest and optimum evaluation by origin, judging by the bulls’ pedigree (geneological) index. The frequency to meet bulls with the desired mixed genotypes was low and amounted to 4.28–5.71 %.

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Molecular genetic markers of economically important traits in dairy cattle

Cited by 27 publications

References 80 publications

Comparative analysis of allele frequencies for DNA polymorphisms associated with disease and economically important traits in the genomes of Russian and foreign cattle breeds

Comparative analysis of allele frequencies for DNA polymorphisms associated with disease and economically important traits in the genomes of Russian and foreign cattle breeds

The effect of holstein bulls’kappa-casein gene genotype on the productive longevity of their female offspring in the republic of Bashkortostan

Evaluation towards stud bulls with different mixed genotypes relating to somatotropin cascade genes by origin

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