Molecular Evolution of the Myb Family of Transcription Factors: Evidence for Polyphyletic Origin

Rosinski, James; Atchley, William R.

doi:10.1007/pl00006285

Cited by 271 publications

(205 citation statements)

References 30 publications

(30 reference statements)

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“…The third heterogeneous class comprises proteins with a single or a partial MYB repeat, collectively designated "MYB-related" that fall into several subclasses (Rosinski and Atchley 1998). Most plant MYB genes encode proteins of the R2R3MYB class, which are thought to have evolved from an R1R2R3-MYB gene ancestor, by the loss of the sequences encoding the R1 repeat and subsequent expansion of the gene family (Rosinski and Atchley 1998).…”

Section: Evolution Of Mybmentioning

confidence: 99%

“…Most plant MYB genes encode proteins of the R2R3MYB class, which are thought to have evolved from an R1R2R3-MYB gene ancestor, by the loss of the sequences encoding the R1 repeat and subsequent expansion of the gene family (Rosinski and Atchley 1998). However, the evolution of 3R-MYB genes from R2R3-MYB genes by the gain of the sequences encoding the R1 repeat through an ancient intragenic duplication has also been proposed (Jiang et al 2004b).…”

Section: Evolution Of Mybmentioning

confidence: 99%

See 1 more Smart Citation

MYB transcription factor genes as regulators for plant responses: an overview

Ambawat

Sharma

Yadav

et al. 2013

Physiol Mol Biol Plants

822

544

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Regulation of gene expression at the level of transcription controls many crucial biological processes. Transcription factors (TFs) play a great role in controlling cellular processes and MYB TF family is large and involved in controlling various processes like responses to biotic and abiotic stresses, development, differentiation, metabolism, defense etc. Here, we review MYB TFs with particular emphasis on their role in controlling different biological processes. This will provide valuable insights in understanding regulatory networks and associated functions to develop strategies for crop improvement.

show abstract

Section: Evolution Of Mybmentioning

confidence: 99%

Section: Evolution Of Mybmentioning

confidence: 99%

MYB transcription factor genes as regulators for plant responses: an overview

Ambawat

Sharma

Yadav

et al. 2013

Physiol Mol Biol Plants

822

544

View full text Add to dashboard Cite

show abstract

“…The MYB domain consists of two or three 50-to 53-amino acid imperfect repeats that form the helixturn-helix motifs R1, R2, and R3 (Rosinsky and Atchley, 1998). MYB proteins in animals generally contain three repeats having significant structural homology to cellular proto-oncogenes and play roles in cell cycle control (Lipsick, 1996).…”

mentioning

confidence: 99%

Overexpression of AtMYB44 Enhances Stomatal Closure to Confer Abiotic Stress Tolerance in Transgenic Arabidopsis

et al. 2007

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AtMYB44 belongs to the R2R3 MYB subgroup 22 transcription factor family in Arabidopsis (Arabidopsis thaliana). Treatment with abscisic acid (ABA) induced AtMYB44 transcript accumulation within 30 min. The gene was also activated under various abiotic stresses, such as dehydration, low temperature, and salinity. In transgenic Arabidopsis carrying an AtMYB44 promoterdriven b-glucuronidase (GUS) construct, strong GUS activity was observed in the vasculature and leaf epidermal guard cells. Transgenic Arabidopsis overexpressing AtMYB44 is more sensitive to ABA and has a more rapid ABA-induced stomatal closure response than wild-type and atmyb44 knockout plants. Transgenic plants exhibited a reduced rate of water loss, as measured by the fresh-weight loss of detached shoots, and remarkably enhanced tolerance to drought and salt stress compared to wild-type plants. Microarray analysis and northern blots revealed that salt-induced activation of the genes that encode a group of serine/threonine protein phosphatases 2C (PP2Cs), such as ABI1, ABI2, AtPP2CA, HAB1, and HAB2, was diminished in transgenic plants overexpressing AtMYB44. By contrast, the atmyb44 knockout mutant line exhibited enhanced salt-induced expression of PP2C-encoding genes and reduced drought/salt stress tolerance compared to wild-type plants. Therefore, enhanced abiotic stress tolerance of transgenic Arabidopsis overexpressing AtMYB44 was conferred by reduced expression of genes encoding PP2Cs, which have been described as negative regulators of ABA signaling.

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“…A transcription factor is composed of a DNA-binding domain and a catalytic (activation or repression) domain. MYB transcription factors contain a con-served DNA-binding domain consisting of two or three imperfect repeats of 50-53-amino acids (R1, R2 and R3) that form the helix-turn-helix motifs (Peters et al, 1987;Rosinsky and Atchley, 1998).…”

Section: Introductionmentioning

confidence: 99%