Molecular evolution of the hypervariable region of the attachment glycoprotein gene in human respiratory syncytial virus subgroup B genotypes BA9 and BA10

Nagasawa, Kinzo; Hirano, Eiko; Kobayashi, Miho; Ryo, Akihide; Oishi, Kazunori; Obuchi, Masatsugu; Ishiwada, Naruhiko; Noda, Masahiro; Kuroda, Makoto; Shimojo, Naoki; Kimura, Hirokazu

doi:10.1016/j.meegid.2015.09.020

Cited by 14 publications

(22 citation statements)

References 36 publications

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“…To construct a phylogenic tree and estimate the evolutionary rate of the F gene, Bayesian Markov chain Monte Carlo (MCMC) method was used, as previously described (Hirano et al, 2014;Kushibuchi et al, 2013;Nagasawa et al, 2015). In this phylogenetic analysis, we used all screened HRSV-A strains (246 strains) and two reference strains, CH18537 (a prototype HRSV-B strain, accession no.…”

Section: Phylogenetic Tree Of the Hrsv-a F Genementioning

confidence: 99%

“…In addition, we calculated the level of the deduced amino acid similarity using the Kimura 2-parameter method with a window size of 40 residues and a step size of two residues. In addition to estimating the frequency distribution of the F gene in each cluster of strains, the p-distances were calculated using MEGA 6.0, as reported previously (Hirano et al, 2014;Nagasawa, et al, 2015;Tamura et al, 2013).…”

Section: Accepted Manuscriptmentioning

confidence: 99%

“…2. (Drummond and Rambaut, 2007;Drummond et al, 2005;Nagasawa et al, 2015). The best substitution models for these analyses were selected using…”

Section: Bayesian Skyline Plot Analysesmentioning

confidence: 99%

“…We attempted to identify positive and negative selection sites using all methods described in previous reports (Botosso et al, 2009;Kobayashi et al, 2015;Nagasawa et al, 2015). No…”

Section: Positive and Negative Selection Site Analysesmentioning

confidence: 99%

“…HRSV-A and -B have been further classified into 12 genotypes (GA1-7, SAA1, NA1, NA2, ON1, and ON2) and 21 genotypes (GB1-4, BA1-11, SAB1-4, and URU1-2), respectively (Cui et al, 2013;Hirano et al, 2014;Nagasawa et al, 2015). However, a recent report suggests that HRSV-A can be classified into seven genotypes (GA1-7; Trento et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

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Molecular evolution of the fusion protein gene in human respiratory syncytial virus subgroup A

Kimura

Nagasawa

Tsukagoshi

et al. 2016

Infection, Genetics and Evolution

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Section: Phylogenetic Tree Of the Hrsv-a F Genementioning

confidence: 99%

Section: Accepted Manuscriptmentioning

confidence: 99%

“…2. (Drummond and Rambaut, 2007;Drummond et al, 2005;Nagasawa et al, 2015). The best substitution models for these analyses were selected using…”

Section: Bayesian Skyline Plot Analysesmentioning

confidence: 99%

“…We attempted to identify positive and negative selection sites using all methods described in previous reports (Botosso et al, 2009;Kobayashi et al, 2015;Nagasawa et al, 2015). No…”

Section: Positive and Negative Selection Site Analysesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Molecular evolution of the fusion protein gene in human respiratory syncytial virus subgroup A

Kimura

Nagasawa

Tsukagoshi

et al. 2016

Infection, Genetics and Evolution

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Genetic variability of human respiratory syncytial virus group B in Panama reveals a novel genotype BA14

Ábrego

Delfraro

Franco³

et al. 2017

Journal of Medical Virology

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In Panama, human respiratory syncytial virus (HRSV) is responsible of 20-40% of acute respiratory infections in children under 5 years old. Currently, little is known about the genetic variability of HRSV in Central America and the Caribbean. Recently, we reported the genetic variability of HRSV-A, however; no studies on HRSV-B in Panama have been described yet. In this study, 24 sequences of Panamanian HRSV-B, from children (<5 years) with acute respiratory infections (ARI), collected from July 2008 to November 2012 were analyzed. All sequences share the characteristic 60-nt duplication of the BA strains. Six Panamanian strains grouped with the BA10 genotype and 12 samples clustered together in a separate monophyletic clade with an aLRT support value of 0.92 and an intra-group p-distance less than 0.07. This fulfills the criteria to consider a new genotype in HRSV, which we named BA14 genotype. Another six strains remain unclassified, but closely related to BA9, BA11, or the new BA14 genotypes, according to their genetic p-distance. Different amino acid substitutions in the Panamanian HRSV-B strains were observed, some previously described and others found only on Panamanian strains. This study contributes to the knowledge of the genetic variability and evolution of HRSV in Central America.

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Genetic diversity and molecular epidemiology of respiratory syncytial virus circulated in Antananarivo, Madagascar, from 2011 to 2017: Predominance of ON1 and BA9 genotypes

Rahombanjanahary

Rybkina

Randriambolamanantsoa

et al. 2020

Journal of Clinical Virology

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Molecular evolution of the hypervariable region of the attachment glycoprotein gene in human respiratory syncytial virus subgroup B genotypes BA9 and BA10

Cited by 14 publications

References 36 publications

Molecular evolution of the fusion protein gene in human respiratory syncytial virus subgroup A

Molecular evolution of the fusion protein gene in human respiratory syncytial virus subgroup A

Genetic variability of human respiratory syncytial virus group B in Panama reveals a novel genotype BA14

Genetic diversity and molecular epidemiology of respiratory syncytial virus circulated in Antananarivo, Madagascar, from 2011 to 2017: Predominance of ON1 and BA9 genotypes

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