Molecular epidemiology of HIV, HBV, HCV, and HTLV-1/2 in drug abuser inmates in central Javan prisons, Indonesia

Prasetyo, Afiono Agung; Dirgahayu, Paramasari; Sari, Yulia; Hudiyono, Hudiyono; Kageyama, Seiji

doi:10.3855/jidc.2965

Cited by 58 publications

(35 citation statements)

References 42 publications

(50 reference statements)

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“…The result of low investment in care and little political will to implement efforts to try to solve existing problems is clear. Health care in prisons is solely the responsibility of prison administration, and is disconnected from the recommendations laid down in the protocols of public health programs (11)(12)(13)(14) . Although international organizations have shown a decline in the rate of HIV prevalence among prisoners, reaching an average of 3.0% a year (15) , official data indicate that it is still higher than in the general population, demonstrating that it is a public health problem that is difficult to tackle.…”

Section: Discussionmentioning

confidence: 99%

“…The determinant risk factors that affect the health needs of prison populations include: overpopulation; unsafe sexual practices, especially those involving violence; use of drugs; and sharing sharp objects (12)(13)(14) . Regarding drug use, more than half of those infected with HIV reported using or having used drugs at some point in their lives.…”

Section: Discussionmentioning

confidence: 99%

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Fatores associados à prevalência do vírus da imunodeficiência humana em população privada de liberdade

Sousa

Araújo

Teles

et al. 2017

Rev. esc. enferm. USP

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Objective:To analyze HIV prevalence and associated factors in inmates in a prison in a state in the Northeast region of Brazil. Method: Epidemiological, cross-sectional study carried out with prisoners. Interviews were conducted using a form and a rapid test for the diagnosis. Bivariate and multivariate hypothesis testing, with a simple logistic ratio (unadjusted odds ratio) and multiple ratio (adjusted odds ratio) were applied. Significance level was set at p≤0.05. Results: A total of 2,131 inmates participated in the study. The HIV prevalence was 1.0%. Seropositive individuals were mostly Afro-American; their marital status was predominantly single/separated/widower. The mean age was of 31.3 years, and the mean educational level was 6.29 years. There was a link between the HIV virus and the variables: selection of partners based on physical attributes and vaginal sexual intercourse. Conclusion: Tackling the HIV infection represents a major challenge for prison and sanitary authorities, considering that the issues related to the HIV context inside and outside the prison environment are interconnected and, therefore, demands coordinated action.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Fatores associados à prevalência do vírus da imunodeficiência humana em população privada de liberdade

Sousa

Araújo

Teles

et al. 2017

Rev. esc. enferm. USP

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show abstract

“…Environmental factors like overcrowding of PWID, access to drugs, and limited access to NSPs and MMT, facilitate within-prison drug injection (WP-DI) and transmission of blood-borne pathogens (Dolan et al, 2007; Dolan et al, 2014). In Indonesia, prisons therefore may serve as amplifying reservoirs, contributing to HIV transmission in prisons and in communities where prisoners are released (Mathers et al, 2008; Prasetyo et al, 2013). Limited data about WP-DI in Indonesia are available.…”

Section: Introductionmentioning

confidence: 99%

Within-prison drug injection among HIV-infected male prisoners in Indonesia: A highly constrained choice

Culbert¹,

Waluyo²,

Iriyanti³

et al. 2015

Drug and Alcohol Dependence

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Background In Indonesia, incarceration of people who inject drugs (PWID) and access to drugs in prison potentiate within-prison drug injection (WP-DI), a preventable and extremely high-risk behavior that may contribute substantially to HIV transmission in prison and communities to which prisoners are released. Aims This mixed method study examined the prevalence, correlates, and social context of WP-DI among HIV-infected male prisoners in Indonesia. Methods 102 randomly selected HIV-infected male prisoners completed semi-structured voice-recorded interviews about drug use changes after arrest, drug use cues within prison, and impact of WP-DI on HIV and addiction treatment. Logistic regression identified multivariate correlates of WP-DI and thematic analysis of interview transcripts used grounded-theory. Results Over half (56%) of participants reported previous WP-DI. Of those, 93% shared injection equipment in prison, and 78.6% estimated sharing needles with ≥10 other prisoners. Multivariate analyses independently correlated WP-DI with being incarcerated for drug offenses (AOR=3.29, 95%CI=1.30–8.31, p=0.011) and daily drug injection before arrest (AOR=5.23, 95%CI=1.42–19.25, p=0.013). Drug availability and proximity to drug users while incarcerated were associated with frequent drug craving and escalating drug use risk behaviors after arrest. Energetic heroin marketing and stigmatizing attitudes toward methadone contribute to WP-DI and impede addiction and HIV treatment. Conclusions Frequent WP-DI and needle sharing among these HIV-infected Indonesian prison inmates indicate the need for structural interventions that reduce overcrowding, drug supply, and needle sharing, and improve detection and treatment of substance use disorders upon incarceration to minimize WP-DI and associated harm.

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“…Since 2009, our group has been conducting a molecular epidemiology study of human blood-borne viruses, by collecting epidemiological-clinical data and blood samples from the highrisk communities (men having sex with men [20], drug abuser inmates in prisons [21] and jails, commercial sex workers, injection drug users, and people engaging in heterosexual contact with HIV-positive partners) in Central Java, Indonesia. All collected blood samples were subjected to hematological and HIV [20] assays, and then fractionated, aliquoted, and kept frozen until analysis.…”

Section: Study Populationmentioning

confidence: 99%

“…The viral nucleic acid extraction and molecular detection techniques were performed as described previously with minor modifications [21]. Briefly, a portion of the HIV gag gene encoding the p24 region was amplified by nested PCR.…”

Section: Nucleic Acid Extraction and Molecular Detectionmentioning

confidence: 99%

The APOBEC3B deletion polymorphism is associated with prevalence of hepatitis B virus, hepatitis C virus, Torque Teno virus, and Toxoplasma gondii co-infection among HIV-infected individuals

Prasetyo

Sariyatun

Reviono

et al. 2015

Journal of Clinical Virology

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Molecular epidemiology of HIV, HBV, HCV, and HTLV-1/2 in drug abuser inmates in central Javan prisons, Indonesia

Cited by 58 publications

References 42 publications

Fatores associados à prevalência do vírus da imunodeficiência humana em população privada de liberdade

Fatores associados à prevalência do vírus da imunodeficiência humana em população privada de liberdade

Within-prison drug injection among HIV-infected male prisoners in Indonesia: A highly constrained choice

The APOBEC3B deletion polymorphism is associated with prevalence of hepatitis B virus, hepatitis C virus, Torque Teno virus, and Toxoplasma gondii co-infection among HIV-infected individuals

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