Molecular Docking Studies on Synthetic Therapeutic Agents for COVID-19

Abstract

Coronavirus disease (COVID-19) is an infectious disease caused by coronavirus 2 (SARS CoV-2) who have been detected for the first time in Wuhan China in December 2019. The rapid spread of this highly contagious and pathogenic virus led to the declaration of the pandemic by the World Health Organization (WHO) on March 11, 2020. In these conditions, the discovery of new antiviral agents is extremely important. For the development of the anti-SARS-CoV-2 drugs, the fastest way is to find potential molecules from the marketed drugs by molecular docking studies.

STUDI PENAMBATAN MOLEKULER SENYAWA FLAVONOID DAUN JAMBU BIJI (Psidium guajava L.) TERHADAP SARS-CoV-2 3CL PROTEASE

“…Penelitian yang dilakukan oleh (Pintilie et al, 2020) melakukan penambatan Molekuler untuk mendapatkan prediksi akurat dari konformasi yang dioptimalkan untuk ligan dan target protein untuk membentuk kompleks yang stabil. Protein yang diigunakan adalah SARS-CoV-2 3CL pro (PDB ID: 6M2N).…”