Molecular detection of virulence markers to identify diarrhoeagenic <i>Escherichia coli</i> isolated from Mula-Mutha river, Pune District, India

Namachivayam, Sivanandan R; Dhawde, Rutuja; Macaden, Ragini; Dias, Mary; Birdi, Tannaz

doi:10.1080/10934529.2021.1930771

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2022

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“…Water is an essential factor for the existence of life. Inadequate sanitary systems, along with unhygienic usage of water, leads to various waterborne acute microbial diarrheal diseases ( 16 , 17 ). Both developing and developed countries are at a risk of infection through waterborne diseases.…”

Section: Discussionmentioning

confidence: 99%

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An Experimental Adult Zebrafish Model for Shigella Pathogenesis, Transmission, and Vaccine Efficacy Studies

et al. 2022

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Shigellosis is a diarrheal disease that is prevalent in developing countries and especially dangerous in young children. Currently, animal models for shigellosis are unable to model some aspects of the infectious cycle. Here, we describe a new shigellosis model in adult zebrafish, an increasingly common model organism for studying bacterial pathogens. The zebrafish model can be used to study Shigella colonization, transmission, and immune responses, as well as test vaccine efficacy.

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Section: Discussionmentioning

confidence: 99%

“…Infections from intracellular pathogens in aquaculture and in natural water bodies have increased in the recent past, and the need for an effective vaccine has become profoundly apparent ( 16 , 17 ). Immune-stimulatory effects of heat-killed bacteria were evaluated in various previous studies ( 11 , 28 ).…”

Section: Discussionmentioning

confidence: 99%