Molecular and Neural Mechanism of Dysphagia Due to Cancer

Okuni, Ikuko; Otsubo, Yuta; Ebihara, Satoru

doi:10.3390/ijms22137033

“…It is listed under code MD93 in the International Classification of Diseases (ICD), 11th revision [2]. OD is a common comorbidity among various patient [3][4][5]. Researchers demonstrated that the prevalence of diagnosed OD was 3% in all adult patients admitted to hospitals in the United States [6] and that it was higher in the population over 75 years old than other age groups [7].…”

Section: Introductionmentioning

confidence: 99%

Strategies of Screening and Treating Post-extubation Dysphagia: An Overview of the Situation in Greek-Cypriot ICUs

Mpouzika¹,

Iordanou²,

Kyranou³

et al. 2023

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Post-extubation dysphagia (PED) can lead to serious health problems in critical ill patients, yet routine bedside screening may be lacking in many Intensive Care Units (ICUs), possibly due to limited awareness for this condition. This study aimed to establish baseline data on the current approaches, the status of perceived best practices to PED screening and treatment, as well as to assess awareness of PED. A nationwide cross-sectional, online survey was conducted of all adult ICUs in the Republic of Cyprus in June 2018. More than 85% of ICUs reported that there was no standard protocol indicating which patients should be screened for PED. Cough reflex testing and water swallow test were the most reported assessment methods used to confirm the presence of PED. Muscle strengthening exercises without swallowing and swallowing exercises were mostly used to treat dysphagia. Overall, 28.6% of the ICUs agreed that PED was common in their unit. We identified gaps in Greek Cypriot ICUs awareness and knowledge regarding PED screening and treatment. Comprehensive unit-based dysphagia education programs must be urgently im-plemented and interdisciplinary and collaborative work between nurses, intensivists and speech and language therapists is needed to address the situation and improve the quality of care pro-vided.

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“…factors of the disease, a considerable number of patients chronically suffer from this condition 6 . Moreover, taste disorder occurring after radiation therapy for cancer of the head and neck and after systemic chemotherapy for other malignancies can be highly refractory to treatment 7 .…”

Section: Introductionmentioning

confidence: 99%

Improving taste sensitivity in healthy adults using taste recall training: a randomized controlled trial

Otsubo

¹

,

Miyagi

²

,

Sekiya

³

et al. 2022

Sci Rep

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Although many patients suffer from taste disorder, methods to improve taste sensitivity are limited. To develop a taste recall training method to improve the perception of taste, 42 healthy individuals were randomly assigned to either the training or the control group. Using the filter paper disc method, participants in the training group were asked to match the four tastes (sweetness, saltiness, sourness, and bitterness) between those of taste recognition thresholds and those of a one-step higher concentration until they get them right. Then, they were asked to match the four tastes between those of one-step lower and one-step higher in concentration from their taste recognition thresholds until they get them right. Finally, they were asked to match the four tastes between those of one-step lower concentration and those of their taste recognition thresholds until they get them right. This training was repeated until perfectly matched. The taste recall training program led to a lowered taste recognition threshold in healthy adults for each taste quality, suggesting the improvement of taste sensitivity. This lowered threshold for each taste was observed with each additional training session. We conclude that this taste recall training method might be a therapeutic approach for treating taste disorder.

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“…factors of the disease, a considerable number of patients chronically suffer from this condition 6 . Moreover, taste disorder occurring after radiation therapy for cancer of the head and neck and after systemic chemotherapy for other malignancies can be highly refractory to treatment 7 .…”

Section: Introductionmentioning

confidence: 99%

Improving Taste Sensitivity in Healthy Adults Using Taste Recall Training: a randomized controlled trial

Otsubo

¹

,

Miyagi

²

,

Sekiya

³

et al. 2022

Preprint

0

View full text Add to dashboard Cite

Although many patients suffer from taste disorder, methods to improve taste sensitivity are limited. To develop a taste recall training method to improve the perception of taste, 42 healthy individuals were randomly assigned to either the training or the control group. Using the filter paper disc method, participants in the training group were asked to match the four tastes (sweetness, saltiness, sourness, and bitterness) between those of taste recognition thresholds and those of a one-step higher concentration until they get them right. Then, they were asked to match the four tastes between those of one-step lower and one-step higher in concentration from their taste recognition thresholds until they get them right. Finally, they were asked to match the four tastes between those of one-step lower concentration and those of their taste recognition thresholds until they get them right. This training was repeated until perfectly matched. The taste recall training program led to a lowered taste recognition threshold in healthy adults for each taste quality, suggesting the improvement of taste sensitivity. This lowered threshold for each taste was observed with each additional training session. We conclude that this taste recall training method might be a therapeutic approach for treating taste disorder.

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Molecular and Neural Mechanism of Dysphagia Due to Cancer

Cited by 11 publications

References 128 publications

Strategies of Screening and Treating Post-extubation Dysphagia: An Overview of the Situation in Greek-Cypriot ICUs

Strategies of Screening and Treating Post-extubation Dysphagia: An Overview of the Situation in Greek-Cypriot ICUs

Improving taste sensitivity in healthy adults using taste recall training: a randomized controlled trial

Improving Taste Sensitivity in Healthy Adults Using Taste Recall Training: a randomized controlled trial

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