Moisturizing effect of a cosmetic formulation containing pequi oil (Caryocar brasiliense) from the Brazilian cerrado biome

Abstract

Caryocar brasiliense, popularly known in Brazil as "pequi", is a species widely distributed in the Brazilian Cerrado. The seeds are surrounded by a woody endocarp coated with a yellow fleshy mesocarp rich in oil and vitamin A, whose oil has a useful role in the treatment of skin aging and protection of human skin against UV-induced damage and skin hydration. The aim of this study was to evaluate the effect of cosmetic formulations containing pequi oil (Caryocar brasiliense) on skin hydration, after a single application. Hydration effect assessment was performed by applying the formulations under study (Control -no formulation, vehicle, and vehicle + pequi oil) onto forearm skin of 30 human volunteers. Skin capacitance and Transepidermal Water Loss (TEWL) measurements were analyzed before, and at 1, 2 and 3 hours after, a single application. Evaluation results of a single application of the vehicle containing pequi oil showed an increase in stratum corneum water content, indicating a skin moisturizing effect. Results of the evaluation of immediate effects of TEWL demonstrated that the vehicle containing pequi oil significantly increased skin moisture during the 3 h evaluation period. The formulations containing pequi oil showed clinical efficacy, increasing stratum corneum water content and enhancing skin barrier function. Caryocar brasiliense, popularmente conhecido como "Pequi", é uma espécie amplamente distribuída no Cerrado Brasileiro. O fruto é composto por sementes com endocarpo rígido e lenhoso, recoberto pelo mesocarpo carnoso, amarelado, rico em óleos e vitamina A, útil na proteção da pele contra raios UV, no tratamento das marcas senis da pele, bem como na hidratação cutânea. O objetivo deste estudo foi avaliar o efeito cosmético de formulações contendo óleo de pequi (Caryocar brasiliense) na hidratação cutânea, após uma única aplicação. Este efeito foi avaliado instrumentalmente através de medidas da capacitância da pele e pela perda de água transepidérmica após 1, 2 e 3 horas de uma única aplicação das formulações em estudo (controle, veículo e veículo + óleo de pequi) na pele do antebraço de 30 voluntários. Por meio das avaliações, a formulação contendo óleo de pequi aumentou o conteúdo de água no estrato córneo após 1, 2 e 3 horas, além de diminuir a perda de água transepidérmica, aumentando, significativamente, a hidratação cutânea durante as 3 horas de avaliação. A formulação contendo óleo de pequi apresentou eficácia clínica, aumentando o conteúdo aquoso do estrato córneo, bem como promovendo o efeito barreira na pele. Unitermos:Caryocar brasiliense/farmacognosia. Caryocar brasiliense/uso cosmético. Óleo de pequi/ formulações cosméticas/efeito. Hidratação cutânea/uso do óleo de pequi.

Short communication: Antimicrobial activity of pequi (Caryocar brasiliense) waste extract on goat Minas Frescal cheese presenting sodium reduction

“…Pequi (Caryocar brasiliense) is a native fruit from Brazil containing high antioxidant concentrations (Faria et al, 2014). Pequi extracts present high antimicrobial activity, inhibiting or delaying microorganism growth, especially concerning spoilage and pathogenic bacteria.…”

Production and Characterization of Cosmetic Nanoemulsions Containing Opuntia ficus-indica (L.) Mill Extract as Moisturizing Agent

“…This study was designed as a one-sided blind, placebo-controlled study. The volunteers were instructed not to use any cosmetic products for two weeks before and on the day of the experiment, except cleaning products like soap [ 57 , 59 ]. Prior to all measurements, volunteers were left in the room for at least 30 min in order to allow full skin adaptation to the room’s temperature (21 ± 2 °C) and relative humidity (60% ± 5%) [ 57 , 59 ].…”

“…C2 had FX formulation (vehicle), C3 had the formulation containing 1.0% of Opuntia ficus-indica hydroglycolic extract—FXE, and a commercial moisturizer was used as positive control in C4. All formulations were applied to the surface of the skin at a dose of 2 mg/cm 2 with a light massage of approximately 10 s [ 57 , 59 ].…”

Use of Opuntia ficus-indica (L.) Mill extracts from Brazilian Caatinga as an alternative of natural moisturizer in cosmetic formulations

“…The volunteers were instructed not to use any cosmetic products for two weeks before and on the day of the experiment, except cleaning products like soap. This methodology was adapted from Faria, Damasceno and Ferrari (2014) and Maia Campos et al (2012). Prior to all measurements, volunteers were left in the room for at least 30 min in order to allow full skin adaptation to the room's temperature (20 ± 2 ºC) and humidity (60 ± 5%).…”