Möglichkeiten und Grenzen der Diphtherieserumwirkung

The Types Mitis, Intermedius and Gravis of Corynebacterium Diphtheriae

“…Although so high a case death rate has been uncommon, similar observations have been recorded in many quarters. This has been so in a quite special degree in Germany where it is emphasized amongst others by K6nigsberger (94), Wolter (198), Gundel (64), Paschlau and Sudhues (134), Degkwitz (36), and Woldrich (197). Rostoski (153) points out that in Germany the incidence of diphtheria rose from 30,000 in 1926 to 150,000 in 1936.…”

“…So much is this the case that a considerable controversy has gone on in the European medical press on the value of antidiphtheritic serum. Thus Friedberger (49), Zischinsky (213) and Hottinger (82) have expressed marked skepticism about its value in the most severe types of diphtheria, and Paschlau and Sudhues (134), who report a 25 per cent mortality amongst malignant cases treated oni the "first day of' dise"ase, even suggest that in such cases serum is valueless unless administered before the second day.…”