MOF(Fe)-derived composites as a unique nanoplatform for chemo-photodynamic tumor therapy

Abstract

Fe-based metal-organic frameworks (MOFs) can be used for chemodynamic therapy (CDT) for tumors due to their unique Fenton-like effects and porous and biodegradable natures. However, the therapeutic effects of using...

Recent advances on g-C3N4-based Z-scheme photocatalysts for organic pollutant removal

“…Hydrothermal and solvothermal approaches are usually conducted in a sealed autoclave under high temperature and pressure conditions, endowing the obtain semiconductors with high crystallinity, regulatable morphology, and homogeneous size distribution. 13,[150][151][152][153][154][155] Therefore, this strategy is commonly utilized for fabricating g-C 3 N 4 -based Z-scheme photocatalysts without further post-treatment. Liu and co-workers 156 reported on Bi 2 WO 6 quantum dots/g-C 3 N 4 binary Z-scheme systems via a simple one-pot hydrothermal strategy.…”

Tumor Cell Targeting and Responsive Nanoplatform for Multimodal-Imaging Guided Chemodynamic/Photodynamic/Photothermal Therapy toward Triple Negative Breast Cancer

“…Moreover, PDA is liable to chelate with the transition metal ions, such as Fe 3+ and Mn 2+ , , making them capable for magnetic resonance imaging (MRI). On the other hand, Fe 3+ can initiate Fenton reaction to produce hydroxyl radical (·OH) for CDT (eqs and ). − Due to these advantages, PDA-based theranostic biomaterials had been developed, − ,− which provided theoretical foundation and research method for developing theranostic biomaterials. However, these materials exploited only one or two of the aforementioned merits; nanomaterial integrating all these advantages of PDA should have more functions and better performance in the tumor theranostics, which was still lacking and on urgent demand. Fe 3 + + normalH 2 normalO 2 → Fe 2 + + ·OOH + normalH + Fe 2 + + normalH 2 normalO 2 → Fe 3 + + ·OH + OH − …”

A tunable fluorescent probe for superoxide anion detection during inflammation caused byTreponema pallidum

“…6,7 Indeed, T. pallidum infection initially destructs the tissue and triggers an inflammatory response, 8–10 which subsequently activate the production of reactive oxygen species (ROS) to promote the phagocytosis and clearance by macrophages. 8,11–16 The overload ROS plays a central role in the inflammatory disease due to its contribution to trigger oxidative stress and induce inflammation, 17–19 and superoxide radical (O 2 ˙ − ), a primary ROS, 20 has been usually used as a biomarker of inflammation diagnosis. 21,22 The dysregulated O 2 ˙ − can lead to oxidative stress, 23 causing harm to biomolecules like DNA, proteins and lipids and inducing apoptosis.…”

“…6,7 Indeed, T. pallidum infection initially destructs the tissue and triggers an inflammatory response, [8][9][10] which subsequently activate the production of reactive oxygen species (ROS) to promote the phagocytosis and clearance by macrophages. 8,[11][12][13][14][15][16] The overload ROS plays a central role in the inflammatory disease due to its contribution to trigger oxidative stress and induce inflammation, [17][18][19] and superoxide radical (O 2…”