Modulatory effect of betaine on expression dynamics of HSPs during heat stress acclimation in goat ( Capra hircus )

Dangi, S.S.; Dangi, Saroj K.; Chouhan, V.S.; Verma, Megha; Kumar, Puneet; Singh, Gyanendra; Sarkar, Mihir

doi:10.1016/j.gene.2015.09.031

Cited by 45 publications

(40 citation statements)

References 31 publications

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Section: Resultsmentioning

confidence: 97%

“…Additionally, it inhibits lipid peroxidation and protects the enzymatic antioxidant defense mechanisms ameliorating the tissue and cellular effect of stress (Dangi et al . ). The LD and haplotype structures in this gene region were found to be different between African and commercial cattle populations, that African cattle populations exhibited stronger LD (Fig.…”

Section: Resultsmentioning

confidence: 97%

“…Betaine has a modulatory effect on HSPs during heat stress; it declines the effect of HSPs by stabilizing cellular proteins and protecting them from heat stress induced denaturation (Dangi et al 2016). Additionally, it inhibits lipid peroxidation and protects the enzymatic antioxidant defense mechanisms ameliorating the tissue and cellular effect of stress (Dangi et al 2016). The LD and haplotype structures in this gene region were found to be different between African and commercial cattle populations, that African cattle populations exhibited stronger LD (Fig.…”

Section: Heat Shock and Oxidative Stress Response Proteinsmentioning

confidence: 97%

“…The osmolytic property of betaine permits cellular adaptation to adverse osmotic environments noticed in hot and humid climates (http://www.wattagnet.com/articles/583-betaine-playsmany-roles-in-broiler-diets). Betaine has a modulatory effect on HSPs during heat stress; it declines the effect of HSPs by stabilizing cellular proteins and protecting them from heat stress induced denaturation (Dangi et al 2016). Additionally, it inhibits lipid peroxidation and protects the enzymatic antioxidant defense mechanisms ameliorating the tissue and cellular effect of stress (Dangi et al 2016).…”

Section: Heat Shock and Oxidative Stress Response Proteinsmentioning

confidence: 99%

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Whole genome detection of signature of positive selection in African cattle reveals selection for thermotolerance

Taye

Lee

Caetano-Anollés

et al. 2017

Animal Science Journal

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As African indigenous cattle evolved in a hot tropical climate, they have developed an inherent thermotolerance; survival mechanisms include a light-colored and shiny coat, increased sweating, and cellular and molecular mechanisms to cope with high environmental temperature. Here, we report the positive selection signature of genes in African cattle breeds which contribute for their heat tolerance mechanisms. We compared the genomes of five indigenous African cattle breeds with the genomes of four commercial cattle breeds using cross-population composite likelihood ratio (XP-CLR) and cross-population extended haplotype homozygosity (XP-EHH) statistical methods. We identified 296 (XP-EHH) and 327 (XP-CLR) positively selected genes. Gene ontology analysis resulted in 41 biological process terms and six Kyoto Encyclopedia of Genes and Genomes pathways. Several genes and pathways were found to be involved in oxidative stress response, osmotic stress response, heat shock response, hair and skin properties, sweat gland development and sweating, feed intake and metabolism, and reproduction functions. The genes and pathways identified directly or indirectly contribute to the superior heat tolerance mechanisms in African cattle populations. The result will improve our understanding of the biological mechanisms of heat tolerance in African cattle breeds and opens an avenue for further study.

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Section: Resultsmentioning

confidence: 97%

Section: Resultsmentioning

confidence: 97%

Section: Heat Shock and Oxidative Stress Response Proteinsmentioning

confidence: 97%

Section: Heat Shock and Oxidative Stress Response Proteinsmentioning

confidence: 99%

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Whole genome detection of signature of positive selection in African cattle reveals selection for thermotolerance

Taye

Lee

Caetano-Anollés

et al. 2017

Animal Science Journal

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“…RR was found to increase in both genetic groups under heat treatment and the increase in Crossbred was found to be significantly (P<0.05) different from that in Tharparkar. A positive correlation exists between RR and heat treatment [28][29][30]. This increase is an attempt to dissipate excess body heat by vaporizing more moisture in expired air or response to a greater requirement of oxygen by tissues under heat stress.…”

Section: Discussionmentioning

confidence: 99%

Systems Biology under heat stress in Indian Cattle

Khan

Sahu

Malla

et al. 2020

Preprint

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BackgroundHeat stress induced by high environmental temperature and humidity affects livestock production and health. With global warming on the uprise, indigenous cattle known for their heat tolerance are gaining importance than the crossbreds. However, systems biology behind this phenotype in indigenous cattle is less known. In this study using transcriptome analysis, we identified key molecules and pathways that may lead to the heat tolerance phenotype in indigenous cattle (Tharparkar breed) Results

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Expression Dynamics of Heat Shock Proteins (HSP) in Livestock under Thermal Stress

Dangi

Bharati

Samad

et al. 2017

Heat Shock Proteins

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Modulatory effect of betaine on expression dynamics of HSPs during heat stress acclimation in goat ( Capra hircus )

Cited by 45 publications

References 31 publications

Whole genome detection of signature of positive selection in African cattle reveals selection for thermotolerance

Whole genome detection of signature of positive selection in African cattle reveals selection for thermotolerance

Systems Biology under heat stress in Indian Cattle

Expression Dynamics of Heat Shock Proteins (HSP) in Livestock under Thermal Stress

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