Abstract:We studied the effect of electrical stimulation of the substantia nigra (SN) on postsynaptic processes evoked in neurons of the somatosensory cortex of the cat by stimulation of nociceptive (intense stimulation of the dental pulp) and non-nociceptive (moderate, in strength, stimulations of the n. infraorbitalis and ventroposteromedial nucleus, VPM, of the thalamus) afferent inputs. The intracellularly recorded 7 cells activated exclusively by stimulation of dental nociceptors and 10 cells activated by both noc… Show more
“…Inhibitory postsynaptic potentials (IPSP) of S1 neurons activated by nociceptive pathways were reduced after stimulation of the substantia nigra (Labakhua et al, 2008). While this may not be mediated by a direct dopaminergic projection to S1, it emphasizes the role of the dopaminergic system in the regulation of SMC inhibition.…”
Section: Modulation Of Sep Amplitudes By D1 and D2 Receptorsmentioning
“…Inhibitory postsynaptic potentials (IPSP) of S1 neurons activated by nociceptive pathways were reduced after stimulation of the substantia nigra (Labakhua et al, 2008). While this may not be mediated by a direct dopaminergic projection to S1, it emphasizes the role of the dopaminergic system in the regulation of SMC inhibition.…”
Section: Modulation Of Sep Amplitudes By D1 and D2 Receptorsmentioning
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