Modulation of Plasma Antioxidant Activity in Weaned Piglets by Plant Polyphenols

Zhang, Hai J.; Jiang, Xianren; Mantovani, G.; Lumbreras, Ana E. Valdez; Comi, Marcello; Alborali, G. L.; Savoini, G.; Dell’Orto, V.; Bontempo, V.

doi:10.4081/ijas.2014.3242

Cited by 30 publications

(31 citation statements)

References 30 publications

(33 reference statements)

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“…Similar results were reported by other authors who observed an improvement in the antioxidant status, an increase in the activity of antioxidant enzymes and a decrease in plasma MDA levels in weaned piglets fed diets supplemented with polyphenols. Dietary polyphenol supplementation improved the health status and growth performance of piglets (Zhang et al 2014;Hao et al 2015;Chen et al 2018).…”

Section: Discussionmentioning

confidence: 99%

The effect of polyphenols on the performance and antioxidant status of sows and piglets

Lipiński

Antoszkiewicz

Mazur-Kuśnirek

et al. 2019

Italian Journal of Animal Science

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ABSRACTThe aim of this study was to determine the efficacy of polyphenols in pigs. The experiment was performed on 52 sows divided into 4 groups. Untreated control sows (group 1) were not administered vitamin E in the premixes. The diets of the experimental animals were supplemented with vitamin E in the amount of 50 mg (group 2) or 100 mg/kg diets (group 3) (gestation diets) and 75 mg (group 2) or 150 mg/kg diets (group 3) (lactation diets). The diets of group four sows were supplemented with vitamin E (50/75 mg/kg, gestation/lactation) and Proviox (polyphenols) (50/75 mg/kg, gestation/lactation). The influence of different dietary inclusion levels of vitamin E and vitamin E/polyphenols on the performance, vitamin E concentrations, and antioxidant status of sows and piglets was analysed. The sows whose diets were supplemented with vitamin E and polyphenols (50:50) were characterised by similar fertility, mating success, and litter performance as the group whose diets were supplemented with vitamin E only. The results of this study indicate that sows receiving vitamin E and polyphenols and their progeny were characterised by similar or improved vitamin E status and improved antioxidant status compared with the animals whose diets were supplemented with 100 mg/150 mg of vitamin E/kg diet. It can be concluded that the replacement of 50% of dietary vitamin E with polyphenols did not compromise the growth performance of sows or piglets and improved their antioxidant status.

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Section: Discussionmentioning

confidence: 99%

The effect of polyphenols on the performance and antioxidant status of sows and piglets

Lipiński

Antoszkiewicz

Mazur-Kuśnirek

et al. 2019

Italian Journal of Animal Science

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“…In the study of Zhang et al. (), supplementation of a basal diet with a mixture of polyphenols extracted from apple, grapes, green tea and olive leaves (at a level of 1 g/kg diet) reduced concentration of MDA in plasma of weaned piglets but had no effect on the total antioxidative capacity and activities of several antioxidant enzymes in plasma. The overall conclusion of the few studies performed so far is that supplementation of polyphenols improves the antioxidative status and ameliorates oxidative stress in pigs subjected to prooxidative treatment.…”

Section: Effects Of Polyphenols On Oxidative Stress and Inflammationmentioning

confidence: 98%

Potential of plant polyphenols to combat oxidative stress and inflammatory processes in farm animals

Geßner

Ringseis

Eder

2016

Animal Physiology Nutrition

249

198

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Polyphenols are secondary plant metabolites which have been shown to exert antioxidative and antiinflamma tory effects in cell culture, rodent and human studies. Based on the fact that conditions of oxidative stress and inflammation are highly relevant in farm animals, polyphenols are considered as promising feed additives in the nutrition of farm animals. However, in contrast to many studies existing with model animals and humans, potential antioxidative and antiinflammatory effects of polyphenols have been less investigated in farm animals so far. This review aims to give an overview about potential antioxidative and antiinflammatory effects in farm animals. The first part of the review highlights the occurrence and the consequences of oxidative stress and inflammation on animal health and performance. The second part of the review deals with bioavailability and metabolism of polyphenols in farm animals. The third and main part of the review presents an overview of the findings from studies which investigated the effects of polyphenols of various plant sources in pigs, poultry and cattle, with particular consideration of effects on the antioxidant system and inflammation.

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“…Proanthocyanidins extracted from other plants have also aroused interest because of their uses in animal nutrition. Park et al (2011), for example, reported that a proanthocyanidin-rich extract from Pinus radiata bark modulates immunity in chickens, whereas Zhang et al (2014) have shown that a prepared plant polyphenol mixture increases the antioxidant ability of plasma in piglets.…”

Section: Introductionmentioning

confidence: 99%

Effects of dietary grape proanthocyanidins on the growth performance, jejunum morphology and plasma biochemical indices of broiler chicks

Yang

Zhang

Wang

et al. 2017

Animal

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Grape proanthocyanidins (GPCs) are a family of naturally derived polyphenols that have aroused interest in the poultry industry due to their versatile role in animal health. This study was conducted to investigate the potential benefits and appropriate dosages of GPCs on growth performance, jejunum morphology, plasma antioxidant capacity and the biochemical indices of broiler chicks. A total of 280 newly hatched male Cobb 500 broiler chicks were randomly allocated into four treatments of seven replicates each, and were fed a wheat-soybean meal-type diet with or without (control group), 7.5, 15 or 30 mg/kg of GPCs. Results show that dietary GPCs decrease the feed conversion ratio and average daily gain from day 21 to day 42, increase breast muscle yield by day 42 and improve jejunum morphology between day 21 and day 42. Chicks fed 7.5 and 15 mg/kg of GPCs show increased breast muscle yield and exhibit improved jejunum morphologies than birds in the control group. Dietary GPCs fed at a level of 15 mg/kg markedly increased total superoxide dismutase (T-SOD) activity between day 21 and day 42, whereas a supplement of GPCs at 7.5 mg/kg significantly increased T-SOD activity and decreased lipid peroxidation malondialdehyde content by day 42. A supplement of 30 mg/kg of GPCs has no effect on antioxidant status but adversely affects the blood biochemical indices, as evidenced by increased creatinine content, increased alkaline phosphatase by day 21 and increased alanine aminotransferase by day 42 in plasma. GPC levels caused quadratic effect on growth, jejunum morphology and plasma antioxidant capacity. The predicted optimal GPC levels for best plasma antioxidant capacity at 42 days was 13 to 15 mg/kg, for best feed efficiency during grower phase was 16 mg/kg, for best jejunum morphology at 42 days was 17 mg/kg. In conclusion, GPCs (fed at a level of 13 to 17 mg/kg) have the potential to be a promising feed additive for broiler chicks.

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Modulation of Plasma Antioxidant Activity in Weaned Piglets by Plant Polyphenols

Cited by 30 publications

References 30 publications

The effect of polyphenols on the performance and antioxidant status of sows and piglets

The effect of polyphenols on the performance and antioxidant status of sows and piglets

Potential of plant polyphenols to combat oxidative stress and inflammatory processes in farm animals

Effects of dietary grape proanthocyanidins on the growth performance, jejunum morphology and plasma biochemical indices of broiler chicks

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