Modulation of motor-cortex oscillatory activity by painful Aδ- and C-fiber stimuli

Raij, Tuukka T.; Forss, Nina; Stančák, Andrej; Hari, Riitta

doi:10.1016/j.neuroimage.2004.06.036

Cited by 87 publications

(59 citation statements)

References 34 publications

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“…The fMRI has been used to study stimulus-related responses, such as noxious electrical stimulation of the skin or peripheral nerve (Davis, Taylor, Crawley, Wood, & Mikulis, 1997;Davis, Wood, Crawley, & Mikulis, 1995;Oshiro et al, 1998), noxious heat or cold (Apkarian, Darbar, Krauss, Gelnar, & Szeverenyi, 1999;Becerra et al, 1999;Davis, Kwan, Crawley, & Mikulis, 1998;Gelnar, Krauss, Sheehe, Szeverenyi, & Apkarian, 1999;Ploghaus et al, 1999;Raij, Forss, Stancak, & Hari, 2005), mechanical (Disbrow, Buonocore, Antognini, Carstens, & Rowley, 1998), chemical (Maihofner & Handwerker, 2005;Porro, Cettolo, Francescato, & Baraldi, 1998) or visceral stimuli (Binkofski et al, 1998). Brain areas that can be activated include the SI, SII, anterior insula, ACC, thalamus, and cerebellum.…”

Section: Patch-clamp Recording In Vivomentioning

confidence: 99%

“…Brain areas that can be activated include the SI, SII, anterior insula, ACC, thalamus, and cerebellum. With the combination of psychophysical assessment and fMRI, pain-related activations have been obtained in parallel psychophysical sessions (Apkarian et al, 1999) or during the imaging sessions (Davis et al, 1997;Porro et al, 1998;Raij et al, 2005) in order to separate those activations due to the mere presence of a stimulus (due to attention) from those related to the subjects" actual sensory experiences. On the other hand, the relationship and interaction of pain, attention, and anticipation has been demonstrated to activate slightly different areas of the brain (Davis et al, 1997;Ploghaus et al, 1999).…”

Section: Patch-clamp Recording In Vivomentioning

confidence: 99%

“…An example MEG image indicates activation of the primary motor cortex while stimulation is applied at Adelta and C-fiber intensities (Figure 8; (Raij et al, 2005). By using MEG in the study of pain, it demonstrated responses to electrical stimulation of the digit at short latencies in the contralateral SI (at 40 to 60 ms), followed by longer latencies in the ipsilateral and bilateral SII and insula (100 to 250 ms) (Howland, Wakai, Mjaanes, Balog, & Cleeland, 1995), as well as the ACC (Kitamura et al, 1995;Kitamura et al, 1997).…”

Section: Patch-clamp Recording In Vivomentioning

confidence: 99%

See 2 more Smart Citations

The biopsychosocial approach to chronic pain: Scientific advances and future directions.

Gatchel¹,

Peng²,

Peters³

et al. 2007

Psychological Bulletin

2,443

1,828

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The prevalence and cost of chronic pain is a major physical and mental health care problem in the United States today. As a result, there has been a recent explosion of research on chronic pain, with significant advances in better understanding its etiology, assessment and treatment. The purpose of the present article is to provide a review of the most noteworthy developments in the field. The biopsychosocial model is now widely accepted as the most heuristic approach to chronic pain. With this model in mind, a review of the basic neuroscience processes of pain (the bio part of biopsychosocial), as well as the psychosocial factors is presented. This spans research on how psychological and social factors can interact with brain processes to influence health and illness, to the development of new technologies, such as brain imaging, that provide new insights into brain-pain mechanisms.KEY WORDS: biopsychosocial; chronic pain; neuroscience of pain; pain and cognition; pain and emotion Biopsychosocial Approach to Chronic Pain 3The Biopsychosocial Approach to Chronic Pain: Scientific Advances and Future Directions During the past decade, there has been an explosion of research on chronic pain, with significant advances in understanding its etiology, assessment and treatment (Gatchel, 2004; Turk & Monarch, 2002). This research has important health care implications Epidemiological research has shown that chronic pain (loosely defined as prolonged and persistant pain of at least 3-months duration) and chronic recurrent pain (recurrent episodes of pain interspersed with pain free periods extending over months or years) affects 10% -20% of adults in the general population (Blyth et al., 2001; Gureje, Von Korff, Simon & Gater, 1998; Vehaak, Kerssens, Dekker, Sorbi & Bensing, 1998). For example, in a large-scale epidemiological study, Von Korff, Crane, Lane et al. (2005) estimated a 19% prevalence for chronic spinal pain (neck and back) in the U.S. in the previous year, and a 29% lifetime rate. The American Academy of Pain Management (2003) asserted that approximately 57% of all adult Americans reported experiencing recurrent or chronic pain in the past year. About 62% of those individuals reporting being in pain for more than 1 year, and 40% noted that they were constantly in pain. Indeed, as Gatchel (2004) has summarized that pain is a pervasive medical problem: it affects over 50 million Americans and costs more than $70 billion annually in health care costs and lost productivity; it accounts for more than 80% of all physician visits. Moreover, chronic pain is often associated with major comorbid psychiatric disorders and emotional suffering.As the above factors attest, the prevalence and cost of chronic pain is a major physical and mental health care problem in the United States. Moreover, individuals 50 years of age and older are twice as likely to have been diagnosed with chronic pain (Gatchel, 2004;. Currently, there are approximately 35 million Americans aged 65 years or older, accounting for 12.4% of t...

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Section: Patch-clamp Recording In Vivomentioning

confidence: 99%

Section: Patch-clamp Recording In Vivomentioning

confidence: 99%

Section: Patch-clamp Recording In Vivomentioning

confidence: 99%

See 1 more Smart Citation

The biopsychosocial approach to chronic pain: Scientific advances and future directions.

Gatchel¹,

Peng²,

Peters³

et al. 2007

Psychological Bulletin

2,443

1,828

View full text Add to dashboard Cite

show abstract

“…Firstly transcranial stimulation of the M1 may alter intracortical motor circuitry. According to Raij et al, high frequency rTMS (10 Hz) was found to re-establish intracortical inhibition in parallel with pain relief [23]. This inhibition of M1 activity was related to the existence of 20 Hz frequency cortical oscillations that are eliminated in the presence of chronic pain.…”

Section: Article In Pressmentioning

confidence: 98%

Transcranial direct current stimulation (tDCS) priming of 1Hz repetitive transcranial magnetic stimulation (rTMS) modulates experimental pain thresholds

Moloney

Witney

2013

Neuroscience Letters

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“…Due to the widespread distribution of the BBA suppression, we cannot disentangle whether the reported effects mostly reflect processing in the motor cortex or processing in somatosensory areas. Previous studies showed that nociceptive stimuli cause a reduction of ongoing ϳ20 Hz oscillations both in the primary motor cortex (Raij et al, 2004) and in somatosensory areas (Ploner et al, 2006a). Thus, it may be that the sensorimotor BBA reflect parallel processing in somatosensory and motor areas, which form a functional network through coupling of neuronal populations (Schnitzler et al, 2000;Brovelli et al, 2002).…”

Section: Pain-induced Beta-band Responsesmentioning

confidence: 99%

Emotional Facial Expressions Modulate Pain-Induced Beta and Gamma Oscillations in Sensorimotor Cortex

Senkowski

Kautz²,

Hauck³

et al. 2011

J. Neurosci.

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Painful events in our environment are often accompanied by stimuli from other sensory modalities. These stimuli may influence the perception and processing of acute pain, in particular when they comprise emotional cues, like facial expressions of people surrounding us. In this whole-head magnetoencephalography (MEG) study, we examined the neuronal mechanisms underlying the influence of emotional (fearful, angry, or happy) compared to neutral facial expressions on the processing of pain in humans. Independent of their valence, subjective pain ratings for intracutaneous inputs were higher when pain stimuli were presented together with emotional facial expressions than when they were presented with a neutral facial expression. Source reconstruction using linear beamforming revealed pain-induced early (70 -270 ms) oscillatory beta-band activity (BBA; 15-25 Hz) and gamma-band activity (GBA; 60 -80 Hz) in the sensorimotor cortex. The presentation of faces with emotional expressions compared to faces with neutral expressions led to a stronger bilateral suppression of the pain-induced BBA, possibly reflecting enhanced response readiness of the sensorimotor system. Moreover, pain-induced GBA in the sensorimotor cortex was larger for faces expressing fear than for faces expressing anger, which might reflect the facilitation of avoidance-motivated behavior triggered by the concurrent presentation of faces with fearful expressions and painful stimuli. Thus, the presence of emotional cues, like facial expressions from people surrounding us, while receiving acute pain may facilitate neuronal processes involved in the preparation and execution of adequate protective motor responses.

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Modulation of motor-cortex oscillatory activity by painful Aδ- and C-fiber stimuli

Cited by 87 publications

References 34 publications

The biopsychosocial approach to chronic pain: Scientific advances and future directions.

The biopsychosocial approach to chronic pain: Scientific advances and future directions.

Transcranial direct current stimulation (tDCS) priming of 1Hz repetitive transcranial magnetic stimulation (rTMS) modulates experimental pain thresholds

Emotional Facial Expressions Modulate Pain-Induced Beta and Gamma Oscillations in Sensorimotor Cortex

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