Modulation of Macrophages and Response of CD117+ Cells of Different Localization after Liver Damage in Mice

Abstract

We studied the effects of stimulation of mononuclear phagocyte system on the state of CD117(+) hepatocytes of growth zone and CD117(+) hemopoietic stem cells after liver damage. Increased number of CD117(+) hepatocytes and enhanced expression of given antigen was revealed. CD117(+) hemopoietic stem cells respond to the impact by migration to the regenerating organ.