Modulating effects of vanillic acid on circadian pattern of indices of redox homeostasis in N-Methly-N′-Nitro-N-Nitrosoguanidine induced endometrial carcinoma in rats

Bhavani, P.; Subramanian, Perumal; Shanmugapriya, S

doi:10.1080/09291016.2016.1173362

Cited by 5 publications

(2 citation statements)

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“…Thus, vanillic acid enhanced circadian amplitude while cinnamic acid reduced it in rats and mice studies, respectively. [168,169] Resveratrol has been also shown to modulate the expression of clock genes such as Sirt1, Per1, Per2, Bmal1, and REV-ERB𝛼 in different animal studies. [167,170] In addition, gut microbiota may be playing a key role in this interaction between phenolic compounds and biological rhythms.…”

Section: Circadian Influence On the Cardiometabolic Effects Of Phenol...mentioning

confidence: 99%

“…Thus, vanillic acid enhanced circadian amplitude while cinnamic acid reduced it in rats and mice studies, respectively. [ 168 , 169 ] Resveratrol has been also shown to modulate the expression of clock genes such as Sirt1 , Per1 , Per2 , Bmal1 , and REV‐ERBα in different animal studies. [ 167 , 170 ]…”

Section: Circadian Influence On the Cardiometabolic Effects Of Phenol...mentioning

confidence: 99%

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Cardioprotective Properties of Phenolic Compounds: A Role for Biological Rhythms

Torres‐Fuentes

Suárez

Aragonès

et al. 2022

Molecular Nutrition Food Res

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Cardiovascular diseases (CVD) are the leading cause of deaths worldwide and their prevalence is continuously increasing. Available treatments may present several side effects and therefore the development of new safer therapeutics is of interest. Phenolic compounds have shown several cardioprotective properties helpful in reducing different CVD risk factors such as inflammation, elevated blood pressure, hyperlipidemia, or endothelial dysfunction. These factors are significantly influenced by biological rhythms which are in fact emerging as key modulators of important metabolic and physiological processes. Thus, increased events of CVD have been observed under circadian rhythm disruption or in winter versus other seasons. These rhythms can also affect the functionality of phenolic compounds. Indeed, different effects have been observed depending on the administration time or under different photoperiods. Therefore, in this review the focus will be on the potential of phenolic compounds as therapeutics to prevent CVD via biological rhythm modulation.

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Section: Circadian Influence On the Cardiometabolic Effects Of Phenol...mentioning

confidence: 99%

“…Thus, vanillic acid enhanced circadian amplitude while cinnamic acid reduced it in rats and mice studies, respectively. [ 168 , 169 ] Resveratrol has been also shown to modulate the expression of clock genes such as Sirt1 , Per1 , Per2 , Bmal1 , and REV‐ERBα in different animal studies. [ 167 , 170 ]…”

Section: Circadian Influence On the Cardiometabolic Effects Of Phenol...mentioning

confidence: 99%