Modularization of three-dimensional gold nanoparticles/ferrocene/liposome cluster for electrochemical biosensor

Chen, Tingjun; Sheng, Anzhi; Hu, Yong; Mao, Dali; Ning, Limin; Zhang, Juan

doi:10.1016/j.bios.2018.09.101

Cited by 26 publications

(13 citation statements)

References 32 publications

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“…In this cluster, gold nanoparticles, ferrocene, and liposome clusters act as signal amplification components, signal output components, or molecular recognition components. 139 Also, a sensitive DNA-based biosensor (genosensor) was developed for the rapid and selective detection of LPS of E. coli . This system was cost-effective and showed excessive application potential for food safety, environmental monitoring, and real-time diagnosis.…”

Section: Biosensors; Modern Methods For the Recognition Of Lpsmentioning

confidence: 99%

Environmental protection based on the nanobiosensing of bacterial lipopolysaccharides (LPSs): material and method overview

Mobed

Hasanzadeh

2022

RSC Adv.

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Section: Biosensors; Modern Methods For the Recognition Of Lpsmentioning

confidence: 99%

Environmental protection based on the nanobiosensing of bacterial lipopolysaccharides (LPSs): material and method overview

Mobed

Hasanzadeh

2022

RSC Adv.

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“…Despite tremendous progress of electrochemical immunosensors have been achieved, ultra-sensitive high-performance immunosensors with multiple amplified signals are still challenging [ 95 ]. In order to further improve their detection performance and amplify detection signal of CEA, the reducing substrate (o-phenylenediamine[o-PD], Cu 2 O, and Ferrocene[Fc]) and enzyme amplifiers were introduced into the detection system of MoS 2 and H 2 O 2 [ [96] , [97] , [98] , [99] ]. Su et al [ 100 ] used MoS 2 nanocomposites (MoS 2 -AuNPs) decorated with gold nanoparticles to construct an enzyme-assisted signal amplification sensor for CEA analysis.…”

Section: Biosensorsmentioning

confidence: 99%

MoS2-based nanocomposites for cancer diagnosis and therapy

Wang

Li-hua

Huang

et al. 2021

Bioactive Materials

143

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Molybdenum is a trace dietary element necessary for the survival of humans. Some molybdenum-bearing enzymes are involved in key metabolic activities in the human body (such as xanthine oxidase, aldehyde oxidase and sulfite oxidase). Many molybdenum-based compounds have been widely used in biomedical research. Especially, MoS 2 -nanomaterials have attracted more attention in cancer diagnosis and treatment recently because of their unique physical and chemical properties. MoS 2 can adsorb various biomolecules and drug molecules via covalent or non-covalent interactions because it is easy to modify and possess a high specific surface area, improving its tumor targeting and colloidal stability, as well as accuracy and sensitivity for detecting specific biomarkers. At the same time, in the near-infrared (NIR) window, MoS 2 has excellent optical absorption and prominent photothermal conversion efficiency, which can achieve NIR-based phototherapy and NIR-responsive controlled drug-release. Significantly, the modified MoS 2 -nanocomposite can specifically respond to the tumor microenvironment, leading to drug accumulation in the tumor site increased, reducing its side effects on non-cancerous tissues, and improved therapeutic effect. In this review, we introduced the latest developments of MoS 2 -nanocomposites in cancer diagnosis and therapy, mainly focusing on biosensors, bioimaging, chemotherapy, phototherapy, microwave hyperthermia, and combination therapy. Furthermore, we also discuss the current challenges and prospects of MoS 2 -nanocomposites in cancer treatment.

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“…Since their discovery ferrocene (Fc) and its derivatives have been proved to be the excellent chemical reagents in organic and organometallic synthesis, electrochemistry, catalysts, and design of new chiral materials . Nowadays, they have wide applications, for example, medicine, electro‐optical devices, modified electrodes and capacitors, biosensors, and protective coating materials …”

Section: Introductionmentioning

confidence: 99%

2‐[(4‐Aminobutyl)ferrocenylmethylidene]‐5,6‐dimethoxy‐1‐indanone derivatives: Synthesis, characterization, and investigation of electro‐optical properties

Rahimpour

Shafagh‐Azar

Abbasi

et al. 2020

Applied Organom Chemis

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A ferrocenyl‐based, chromophore‐containing 1‐indanone derivative was synthesized through crotonic condensation between 4‐chlorobutylferrocenecarboxaldehyde and 5,6‐dimethoxy‐1‐indanone followed by the nucleophilic substitution of chlorine atom of the obtained dyad with different aromatic and aliphatic amines. The electrochemical and optical properties of the synthesized compounds were investigated to explore the relationship between their structures and optical and electrochemical properties. The bandgaps determined from optical absorption spectra ranged from 2.05 to 2.15 eV. The important electrochemical parameters, including the peak potential separation, peak current ratios, and the dependence of peak currents on the scan rate, were studied. Results showed an electrochemically reversible redox system with diffusion‐controlled redox process for the synthesized compounds. The study of quantum chemistry was performed on the synthesized compounds using the density functional theory approach. The B3LYP method and 6‐311 G(d) basis set were used for optimizing the structures in the gas phase. The theoretical and experimental results show that these compounds can be considered as candidates to be used in optical applications.

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Modularization of three-dimensional gold nanoparticles/ferrocene/liposome cluster for electrochemical biosensor

Cited by 26 publications

References 32 publications

Environmental protection based on the nanobiosensing of bacterial lipopolysaccharides (LPSs): material and method overview

Environmental protection based on the nanobiosensing of bacterial lipopolysaccharides (LPSs): material and method overview

MoS2-based nanocomposites for cancer diagnosis and therapy

2‐[(4‐Aminobutyl)ferrocenylmethylidene]‐5,6‐dimethoxy‐1‐indanone derivatives: Synthesis, characterization, and investigation of electro‐optical properties

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