Modified schirmer test–A screening tool for xerostomia among subjects on antidepressants

Kumar, Nerella Narendra; Panchaksharappa, Mamatha Gowda; Annigeri, Rajeshwari G

doi:10.1016/j.archoralbio.2014.05.008

Cited by 27 publications

(34 citation statements)

References 13 publications

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“…Xerostomia was assessed based on patient's complaints of dry mouth and difficulties in performing oral functions [18,19]. The modified Schirmer's test (MST), performed with sterile paper strips (Schirmer Tear Strips®, ContaCare, Gujarat, India), was used to evaluate the non-stimulated salivary flux (NSSF).…”

Section: Methodsmentioning

confidence: 99%

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Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior

et al. 2017

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ED outpatients were found to present a higher incidence of oral-related complications and an inferior oral health status, compared to gender- and age-matched controls. Alterations verified within outpatients were acknowledged to be quite similar to those previously reported within inpatients, in both of nature and severity, thus sustaining that the cranio-maxillofacial region is significantly affected by ED, even in the early/milder forms of the condition, as expectedly verified within outpatients.

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Section: Methodsmentioning

confidence: 99%

“…The modified Schirmer's test (MST), performed with sterile paper strips (Schirmer Tear Strips®, ContaCare, Gujarat, India), was used to evaluate the non-stimulated salivary flux (NSSF). Subjects with NSSF ≤ 25 mm, following 3 min of collection, were considered to have hyposalivation [19].…”

Section: Methodsmentioning

confidence: 99%

Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior

et al. 2017

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“…It is not clear yet which mechanism is used by these drugs to induce hyposalivation, xerostomia or changes in the salivary composition. 33,47 Owing to the lack of anticholinergic activity of the serotonin uptake inhibitors, it was not believed that a low salivary flow rate and xerostomia would occur. However, there are many other endogenous substance receptors in the salivary glands that mediate the salivary flow rate, such as substance P and vasoactive intestinal peptide receptors.…”

Section: Drugsmentioning

confidence: 99%

“…Tricyclic antidepressants present anticholinergic effects in a variety of degrees. 33,34 They block the effects of acetylcholine on the muscarinic receptors, resulting in a decreased salivary flow rate. Therefore, sympathetic stimulation predominates, which leads to more viscous saliva production.…”

Section: Drugsmentioning

confidence: 99%

Salivary hypofunction: An update on aetiology, diagnosis and therapeutics

Saleh

Figueiredo

Cherubini

et al. 2015

Archives of Oral Biology

193

166

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“…One such newer method is the use of Schirmer tear test strips. [12,13] The present study aims to assess the effect of tobacco on SFR using Schirmer test and salivary pH in subjects having smoking and smokeless form of tobacco habit.…”

mentioning

confidence: 99%

Assessment of salivary flow rate and salivary pH in subjects with smoking and smokeless form of tobacco habits

Shubha¹,

Fasalkar²,

Praveen³

et al. 2018

JMRPS

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Habitual "psychoactive substance (PS) use" is defined as the repeated use of PS, despite the knowledge of its negative health consequences. [1] Some of the readily available PSs are alcohol, tobacco, and arecanut. [2] Tobacco, either as smoked or smokeless form, is one of the most commonly used PS. [3] Smoked tobacco forms are cigarettes, cigars, and loose tobacco in pipes or handmade beedies. [4] Smokeless form of tobacco is available as unflavored tobacco, traditional betel quid, and flavored forms, such as Khaini, Zarda, Mishri, and Datun, or is available in combination with arecanut such as Gutkha and mawa. [4,5] Whether usage of smoked or smokeless tobacco forms have systemic as well as locoregional effects. [6] In oral cavity, saliva is the first biological fluid that gets exposed to the toxic chemicals present in tobacco or arecanut. [5,7] Saliva is a complex secretion of the oral cavity, wherein 93% of volume is secreted by the major salivary glands and remaining 7% is secreted by minor glands. [8] Saliva is composed of 99% of water, 1% of organic and inorganic molecules, and various antibacterial substances. Saliva plays a significant role in maintaining homeostasis of the oral cavity. [8,9] Daily secretion of saliva ranges from 0.75 to 1.5 L/day. Unstimulated whole salivary flow rate (SFR) is about 0.3-0.5 ml/min. The normal pH of saliva ranges from 6.7 to 7.3. The buffering capacity of saliva is an important factor and it usually correlates with flow rate, decrease in the flow rate tends to decrease buffering capacity thereby decreasing the salivary pH (acidic), making the oral mucosa and dental structures more vulnerable to changes, [10] and thus the quantity and quality of saliva are important in maintaining the integrity of oral health. [11] Reduction in the quantity of saliva is known as hyposalivation or xerostomia. Xerostomia is the perceived feeling of dry mouth which may or may not be associated with salivary gland hypofunction. It is subjective and can be measured by means of questionnaires. On the other hand, hyposalivation is a demonstrable reduction in SFR that can be measured objectively by collecting saliva over a specified period of time. Assessment of

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Modified schirmer test–A screening tool for xerostomia among subjects on antidepressants

Cited by 27 publications

References 13 publications

Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior

Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior

Salivary hypofunction: An update on aetiology, diagnosis and therapeutics

Assessment of salivary flow rate and salivary pH in subjects with smoking and smokeless form of tobacco habits

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