Modified Protective Rat Vest

Bc, Cooley

doi:10.1097/00006534-199803000-00051

Cited by 16 publications

(5 citation statements)

References 6 publications

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“…Protective rat vests were applied to all animals to avoid autocannibalization. 15 Both groups were divided into six subgroups of five animals each and each group was reoperated on at different time periods: postoperative 1, 3, 5, 7, 14, and 21 days. In these procedures the grafts were first exposed through the previous incisions under general anesthesia, and patency of the vein grafts was assessed visually.…”

Section: Methodsmentioning

confidence: 99%

Effects of Hematoma on the Short-Term Fate of Experimental Microvenous Autografts

Bayrami̇çli̇

Yilmaz²,

Şan³

et al. 1998

J reconstr Microsurg

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The early effects of hematoma on the healing pattern of interpositional vein grafts were studied in 60 rats. In all animals, vein grafts approximately 10-mm in length were used to bridge defects created in the femoral artery and vein on the same side, with a 1:1 graft-to-host diameter match. Grafted vessels were completely covered with hematoma and separated from the surrounding tissue in 30 animals, while the other 30 rats served as controls. Both groups were divided into six subgroups of five animals each, according to the age of the grafts: 1, 3, 5, 7, 14, and 21 days. Graft patency and healing were assessed both clinically and histologically. 20/30 (66.6 percent) of the interarterial and 27/30 (90 percent) of the intervenous vein grafts in Group 1 (hematoma group), and 28/30 (93.3 percent) of the interarterial and 29/30 (96.6 percent) of the intervenous vein grafts in Group 2 (controls) were found patent. The patency rate of the interarterial vein grafts in the hematoma group was statistically significantly lower than in the control group and than in the intervenous vein grafts of the same group (p<0.005). The majority of interarterial vein-graft failures occurred after postoperative day 7 in Group 1. Patent specimens were examined under scanning electron and light microscopy. The authors concluded that perivascular hematoma caused spasm and flow disturbance, prolonged vessel-wall ischemia, and severe vessel-wall injury in the arterial circulation of the microvenous grafts. It also delayed the healing process and subjected the grafts to the development of occlusive mural thrombus. In contrast, the healing pattern of the intervenous vein grafts was not markedly influenced by perivascular hematoma, and equilibrium between thrombogenic and antithrombogenic factors on the graft surface was restored over a short period of time.

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Section: Methodsmentioning

confidence: 99%

Effects of Hematoma on the Short-Term Fate of Experimental Microvenous Autografts

Bayrami̇çli̇

Yilmaz²,

Şan³

et al. 1998

J reconstr Microsurg

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“…At the end of the surgical procedure, a modified protective rat vest was applied to avoid autocannibalization. 22 Animals were followed up for 12 weeks and thereafter euthanized via an overdose of inhaled isoflurane.…”

Section: Surgical Proceduresmentioning

confidence: 99%

Comparison of Bone Prefabrication with Vascularized Periosteal Flaps, Hydroxyapatite, and Bioactive Glass in Rats

Ersoy

Bayrami̇çli̇

Ercan

et al. 2015

J reconstr Microsurg

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“…Animals were excluded from the study if they developed a hematoma or self mutilated their flap. X-ray paper vests were fashioned to prevent the rat from picking at the suture line 9 .…”

Section: Microvascular Densitymentioning

confidence: 99%

Novel Irradiated Axial Rotational Flap Model in the Rodent

Luginbuhl

Modest

Yan

et al. 2013

JAMA Facial Plast Surg

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Part of the Otolaryngology Commons This Article is brought to you for free and open access by the Jefferson Digital Commons. The Jefferson Digital Commons is a service of Thomas Jefferson University's Center for Teaching and Learning (CTL). The Commons is a showcase for Jefferson books and journals, peer-reviewed scholarly publications, unique historical collections from the University archives, and teaching tools. The Jefferson Digital Commons allows researchers and interested readers anywhere in the world to learn about and keep up to date with Jefferson scholarship. This article has been accepted for inclusion in

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Modified Protective Rat Vest

Cited by 16 publications

References 6 publications

Effects of Hematoma on the Short-Term Fate of Experimental Microvenous Autografts

Effects of Hematoma on the Short-Term Fate of Experimental Microvenous Autografts

Comparison of Bone Prefabrication with Vascularized Periosteal Flaps, Hydroxyapatite, and Bioactive Glass in Rats

Novel Irradiated Axial Rotational Flap Model in the Rodent

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