Modified Osteo-odonto-keratoprosthesis for Treatment of Corneal Blindness

Falcinelli, Giancarlo; Falsini, Benedetto; Taloni, Maurizio; Colliardo, Paolo; Falcinelli, G

doi:10.1001/archopht.123.10.1319

Cited by 206 publications

(134 citation statements)

References 16 publications

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“…Although direct comparison of all these devices is inappropriate because of variations in disease indications and severity, several articles reporting results with these KPros have been published. 28,29,[31][32][33][34][35][36] In assessing these devices, visual outcomes and anatomic success in terms of KPro retention are especially important. Results with OOKP are promising, with good device retention, good visual performance, and relative paucity of devicerelated complications, 35,36 but it is relatively complicated 2(3)-stage procedure insisting return visits to operating room with delayed visual recovery.…”

Section: Discussionmentioning

confidence: 99%

AlphaCor artificial cornea: clinical outcome

Jirásková

Rozsíval

Burova

et al. 2011

Eye

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Purpose The purpose of this study was to describe the long-term results of AlphaCor implantations, and to evaluate the main complications and risk factors. Methods Retrospective analysis of preoperative and follow-up data from 15 AlphaCor implantations. Analysis of outcomes, trends, and associations was performed and compared with data from published clinical trials and a literature review.Results The survival rate of the device at 1, 2, and 3 years was 87%, 58%, and 42%, respectively. Postoperative visual acuity ranged from hand movement to 0.8. The most significant complications were stromal melt (nine cases), optic deposition (three eyes), and retroprosthetic membrane formation (three eyes). The most common device-unrelated complication was trauma (three patients). All complications were managed without loss of the eye. Conclusion AlphaCor provides a treatment option for patients with corneal blindness in which a donor tissue graft would not succeed.

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Section: Discussionmentioning

confidence: 99%

AlphaCor artificial cornea: clinical outcome

Jirásková

Rozsíval

Burova

et al. 2011

Eye

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“…He has also worked with Dr Rao in India 3 years ago to help start the procedure there. The procedure is at present performed only in a few centers in the world [3]. This is a fairly complex procedure, and requires to be performed in 2 stages -each of which can take up to 4 to 6 hours.…”

Section: Modified Ookpmentioning

confidence: 99%

Modified Osteo Odonto Keratoprosthesis (MOOKP) - "Tooth For An Eye"

G.R¹,

Presanthila²

2015

IJOES

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“…[1][2][3] The OOKP is used in the treatment of corneal blindness in diseases with severe ocular inflammation and dry eye (such as end-stage Stevens-Johnson syndrome (SJS), ocular cicatricial pemphigoid, chemical burns, trachoma, dry eyes or multiple corneal graft failure) and has been shown to have good long term retention rates. [4][5] The technique has been previously described in more detail.…”

Section: Introductionmentioning

confidence: 99%

Optical Functional Performance of the Osteo-Odonto-Keratoprosthesis

Lee

Ong

Lam

et al. 2014

Cornea

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This is the accepted version of the paper.This version of the publication may differ from the final published version. Results: Optical analysis showed that the optical cylinder is near diffraction-limited. A reduction in median visual acuity (logMAR) with increasing glare settings was observed from 0.04 (without glare) to 0.20 (with glare at 'High' setting) and significantly reduced statistically when compared to the control group at all levels of glare (P < 0.05). Contrast sensitivity was significantly reduced when compared to age-matched controls at medium and high spatial frequencies (P < 0.05). Median Goldmann perimetry was 65 o (interquartile range 64 -74 o , V4e isopters) and 69 o excluding two glaucomatous subjects. Several vision-related VFQ-25 sub-scales correlated significantly with visual acuity at various BAT levels and contrast sensitivity at medium spatial frequencies, including Dependency, General Vision, Near and Distance Activities. Permanent repository link Conclusions:The OOKP optical cylinder provides patients with a good level of visual acuity that is significantly reduced by glare. We have shown in vivo that updates to the optical cylinder design have improved the patient's field of view. Reduction of glare and refinement of cylinder alignment methods may further improve visual function and patient satisfaction.4

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Modified Osteo-odonto-keratoprosthesis for Treatment of Corneal Blindness

Cited by 206 publications

References 16 publications

AlphaCor artificial cornea: clinical outcome

AlphaCor artificial cornea: clinical outcome

Modified Osteo Odonto Keratoprosthesis (MOOKP) - "Tooth For An Eye"

Optical Functional Performance of the Osteo-Odonto-Keratoprosthesis

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