A rare case of AEPVM is described that was detected following trauma and which gradually improved over 37 months. The EOG showed evidence of generalised RPE dysfunction that resolved and may be useful in the monitoring of AEPVM.
Regular monitoring of renal function and ample fluid intake are important when high doses of aciclovir/valaciclovir are used, even in patients with no previous history of renal failure. Monitoring of serum aciclovir level is useful in those with renal impairment to titrate doses, and high-dose oral valaciclovir should be used with caution.
This is the accepted version of the paper.This version of the publication may differ from the final published version. Results: Optical analysis showed that the optical cylinder is near diffraction-limited. A reduction in median visual acuity (logMAR) with increasing glare settings was observed from 0.04 (without glare) to 0.20 (with glare at 'High' setting) and significantly reduced statistically when compared to the control group at all levels of glare (P < 0.05). Contrast sensitivity was significantly reduced when compared to age-matched controls at medium and high spatial frequencies (P < 0.05). Median Goldmann perimetry was 65 o (interquartile range 64 -74 o , V4e isopters) and 69 o excluding two glaucomatous subjects. Several vision-related VFQ-25 sub-scales correlated significantly with visual acuity at various BAT levels and contrast sensitivity at medium spatial frequencies, including Dependency, General Vision, Near and Distance Activities.
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Conclusions:The OOKP optical cylinder provides patients with a good level of visual acuity that is significantly reduced by glare. We have shown in vivo that updates to the optical cylinder design have improved the patient's field of view. Reduction of glare and refinement of cylinder alignment methods may further improve visual function and patient satisfaction.4
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