Modified electrodes with new phenothiazine derivatives for electrocatyltic oxidation of NADH

Dicu, Delia; Mureşan, Liana Maria; Popescu, Ionel; Cristea, Castelia; Silberg, Ioan A.; Brouant, Pierre

doi:10.1016/s0013-4686(00)00485-0

Cited by 35 publications

(26 citation statements)

References 28 publications

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“…2). This is in contrast to the behavior of DDDP when adsorbed on spectrographic graphite [28,29] (Fig. 2) or on graphite powder incorporated in carbon paste, where a variation of the E8' with pH of around 60 mV per pH unit was registered for both electrodes in agreement with previous results on both graphite and gold [28,29].…”

Section: Electrochemical Behavior Of Modified Electrodessupporting

confidence: 91%

“…The phenothiazine derivative, 16H,18H-dibenzo[c,1]-7,9-dithia-16,18-diazapentacene (DDDP; Figure 1) was available from former studies [28,29]. Zirconium phosphate was synthesized according to previously published procedures [23,26,31].…”

Section: Methodsmentioning

confidence: 99%

“…For each modified electrode, a cyclic voltammogram was recorded, and the surface coverage (G, mol/cm 2 ) was estimated through integration of the area of the wave registered with cyclic voltammetry, assuming an n value equal to 1 [28,29].…”

Section: Dddp Immobilization Onto Graphite Electrodesmentioning

confidence: 99%

“…In the present work, the mechanism of NADH electrooxidation was studied using a phenothiazine derivative, dibenzo-dithia-diazapentacene, (DDDP) [28,29], that was immobilized using three different procedures: adsorption on spectrographic graphite, adsorption on graphite powder and adsorption on ZP. In the last two cases, the modified adsorbents were used to produce carbon paste modified electrodes.…”

Section: Introductionmentioning

confidence: 99%

“…In the last two cases, the modified adsorbents were used to produce carbon paste modified electrodes. This mediator was previously shown to be a 1-electron/1-proton type mediator, which was previously electrochemically characterized when adsorbed on graphite and gold electrodes and also used for electrocatalytic NADH oxidation [28,29]. It was therefore of interest to study the performance of this type of mediator both when adsorbed onto ZP and also when adsorbed onto graphite powder and introduced into carbon paste.…”

Section: Introductionmentioning

confidence: 99%

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NADH Oxidation Using Carbonaceous Electrodes Modified with Dibenzo‐Dithia‐Diazapentacene

et al. 2003

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The electrochemical and the electrocatalytic behavior for NADH oxidation of a newly synthesized phenothiazine derivative, 16H,18H-dibenzo[c,1]-7,9-dithia-16,18-diazapentacene (DDDP), adsorbed on solid spectrographic graphite and on graphite powder or on zirconium phosphate (ZP), both entrapped in carbon paste, were compared. Experiments using cyclic voltammetry and a rotating disk electrode, performed in different experimental conditions (various pH values and NADH concentrations), showed that i) in the pH range between 4 and 8, the E8× value for DDDP adsorbed on ZP becomes pH independent; ii) in contrast to other redox mediators, adsorption of DDDP on ZP induced a significant negative shift of the E8× value; iii) the reaction rate for electrocatalytic oxidation of NADH is markedly increased by adsorbing the mediator on ZP, being further improved by the presence of Ca 2 ions in the solution.

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Section: Electrochemical Behavior Of Modified Electrodessupporting

confidence: 91%

Section: Methodsmentioning

confidence: 99%

Section: Dddp Immobilization Onto Graphite Electrodesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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NADH Oxidation Using Carbonaceous Electrodes Modified with Dibenzo‐Dithia‐Diazapentacene

et al. 2003

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Electropolymerized Materials for Biosensors

Evtugyn

Porfireva

Hianik

2015

Advanced Bioelectronic Materials

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Microwave‐Assisted Catalytic Amination of Phenothiazine; Reliable Access to Phenothiazine Analogues of Tröger's Base

et al. 2013

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Efficient protocols for microwave‐assisted catalyzed amination of halogeno‐phenothiazines are described. Phenothiazine analogues of Tröger's base (PTB) were obtained by condensation of amino‐phenothiazines with formaldehyde in HCl/EtOH/H2O and structurally characterized by NMR and XRD analyses. The formation of PTB isomers was predicted by computational analysis based on theoretical methods (DFT and HF). Electronic properties of the parent amino‐phenothiazines and PTB were assessed on the basis of cyclic voltammetry and UV/Vis absorption/emission spectroscopy data. The compounds exhibit blue fluorescence emission characterized by extremely large Stokes shifts (8900–10300 cm–1) in both dilute solutions and aggregated states. Interactions with different types of biomolecules show the capacity of binding to proteins and DNA, with effects on prooxidant reactivity including lipid peroxidation.

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Modified electrodes with new phenothiazine derivatives for electrocatyltic oxidation of NADH

Cited by 35 publications

References 28 publications

NADH Oxidation Using Carbonaceous Electrodes Modified with Dibenzo‐Dithia‐Diazapentacene

NADH Oxidation Using Carbonaceous Electrodes Modified with Dibenzo‐Dithia‐Diazapentacene

Electropolymerized Materials for Biosensors

Microwave‐Assisted Catalytic Amination of Phenothiazine; Reliable Access to Phenothiazine Analogues of Tröger's Base

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