Modified cylindrical collectors for improved orientation of electrospun nanofibers

Malik, Sairish; Hussain, Tanveer; Nazir, Ahsan; Khenoussi, Nabyl; Cheema, Saeed Ashraf

doi:10.1007/s00289-020-03144-0

Cited by 7 publications

(4 citation statements)

References 29 publications

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“…When there is enough density of electrical charges on the primary network of fibers on the collector, the next fibers that sit sequentially on the collector are repelled and cause the formation of bee nest structures. However, even for conductive collectors, when the fiber subsidence rate is high and the fiber network is sufficiently thick, there will be an accumulation of residual electrical charges on the fiber network, resulting in reduced fiber aggregation, opportunity sufficient steam the solvent remaining on the fibers 73 …”

Section: Effective Parameters Of Electrospinning In Ddsmentioning

confidence: 99%

Altering the characterization of nanofibers by changing the electrospinning parameters and their application in tissue engineering, drug delivery, and gene delivery systems

Ghaderpour

Hoseinkhani

Yarani

et al. 2021

Polymers for Advanced Techs

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Nowadays, nanofibers have various applications in the field of medical biology including drug delivery systems (DDSs) and tissue engineering. Many methods have been developed to produce drug release polymers; the most important and applicable of which is known as electrospinning. In this method, the nanoscale and microscale fibers are used as the functional polymers in the DDSs. A variety of electrospinning methods can be used for delivery systems and tissue engineering. The nanofibers loaded with anticancer drugs have attracted a lot of attention in the last decade. Electrospun parameters include voltage, feed rate, rotary collector, pipette or needle hole diameter, the distance between nozzle tip to collector plate, viscosity and molecular weight of the polymer, surface tension, solubility of polymer, soluble electrical conductivity, dielectric constant, and evaporability of the solution; all could be manipulated to regulate the drug release rate in order via changing the diameter of the nanofibers. In addition to directly loading the drug on nanofibers, the nanoparticles are also used to improve the drug efficacy and reduce the required dose, especially in the case of harmful drugs. Depending on the need, various nanoparticles and nanocarriers are being applied along with the drug. Nanocarriers such as viruses, micelles, and liposomes function highly specific since they carry specific ligands on their surface. Magnetic nanoparticles also have a great therapeutic effect on cancer cells when exposed to heat and magnetic fields. Carbon nanoparticles, such as graphene and graphene oxide, due to their layering, can pass through the cell membrane and deliver the drug to the intracellular space.

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Section: Effective Parameters Of Electrospinning In Ddsmentioning

confidence: 99%

Altering the characterization of nanofibers by changing the electrospinning parameters and their application in tissue engineering, drug delivery, and gene delivery systems

Ghaderpour

Hoseinkhani

Yarani

et al. 2021

Polymers for Advanced Techs

View full text Add to dashboard Cite

show abstract

“…Different modifications have been made to electrospinning systems. Examples of such modifications include the use of rotating drum, 48 parallel electrodes, 49 rotating wire drum collector, 50 drum collector with wire wound on it, 51 rotating tube collector with knife-edge electrodes below, controlling electrospinning jet using knife-edge electrodes, 52 multiple segmented collectors, 53 disc collector, 35,36 array of counter-electrodes, 37,38 rotating drum with sharp pin inside, 54 blade placed in line, king collector placed in parallel, yarn collection using water bath, 55 and multiple spinnerets. 56…”

Section: Electrospinningmentioning

confidence: 99%

Electrospun biomimetic polymer nanofibers as vascular grafts

Malik

Sundarrajan

Hussain

et al. 2020

Mat Design & Process Comms

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Despite all other technologies reported in literature, electrospinning has gained significant importance because of its ability to fabricate nanostructures with distinctive properties, including high surface area and porosity. Electrospinning has been evolved as the most widely used technique in the recent century. It has been employed in various biomedical applications such as tissue-engineered vascular grafts. This can develop fibrous scaffolds that mimic the structure of extracellular matrix of native blood vessels, suitable for the promotion of cell adhesion, proliferation, and cell growth. There is a growing demand for tissue-engineered vascular grafts for the replacement of damaged or defected blood vessels in cardiovascular diseases. The purpose of this review is to summarize recent developments related to electrospun vascular grafts with different synthetic and natural polymers and electrospinning parameters that affect the final properties of vascular grafts. The main focus of this review is also to describe the previously used materials for electrospun vascular grafts and their applications with respect to small and large diameter vascular grafts.

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“…These modifications include multiple-jet electrospinning (single needle, multiple needles, needle-less system), emulsion electrospinning, coaxial electrospinning, drum electrospinning, and porous hollow tube electrospinning. [43][44][45][46]…”

Section: Electrospinning Techniquementioning

confidence: 99%

Sustainable nanofibers in tissue engineering and biomedical applications

Malik

Sundarrajan

Hussain

et al. 2020

Mat Design & Process Comms

Self Cite

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The practice of using a massive amount of environmental unfriendly and toxic petroleum-based materials in tissue engineering and biomedical fields demands the materials, which are biodegradable, renewable, environmentally friendly, biocompatible, and bioactive. So, renewable polymers have got considerable attention due to their numerous desirable properties. The nanofibers that are prepared from renewable materials and their blends can integrate the properties of both nanofibers and renewable polymers. Development of scaffolds that mimic the construction of tissues at nanoscale is a great challenge for tissue engineering. Electrospinning is the most promising technique for nanofibers formation. Nanofibers provide a platform for cell adhesion, proliferation, and differentiation. Therefore, nanofibers from sustainable materials have been used in tissue engineering and biomedical fields. In this review, methods for nanofibers fabrication, sustainable nanofibers made from natural and synthetic polymers and their applications in tissue engineering and biomedical field, have been emphasized.

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Modified cylindrical collectors for improved orientation of electrospun nanofibers

Cited by 7 publications

References 29 publications

Altering the characterization of nanofibers by changing the electrospinning parameters and their application in tissue engineering, drug delivery, and gene delivery systems

Altering the characterization of nanofibers by changing the electrospinning parameters and their application in tissue engineering, drug delivery, and gene delivery systems

Electrospun biomimetic polymer nanofibers as vascular grafts

Sustainable nanofibers in tissue engineering and biomedical applications

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