Modification of the small intestinal submucosa membrane with oligopeptides screened from intrinsically disordered regions to promote angiogenesis and accelerate wound healing
“…A recently discovered promising technique for skin regeneration is the production of biologically decellularized SIS. For example, a team of researchers discovered that the SIS membrane modified with proangiogenic oligopeptide (QSHGPS) can encourage angiogenesis and repair of critical-sized full-thickness wounds on the skin [ 113 ]. As collagen is the primary component of the SIS membrane, scientists construct chimeric peptides utilizing the collagen-binding peptide sequence TKTLRT and the pro-angiogenic oligopeptide sequence QSHGPS.…”
Section: Tissue Repair Using Functional Sismentioning
“…A recently discovered promising technique for skin regeneration is the production of biologically decellularized SIS. For example, a team of researchers discovered that the SIS membrane modified with proangiogenic oligopeptide (QSHGPS) can encourage angiogenesis and repair of critical-sized full-thickness wounds on the skin [ 113 ]. As collagen is the primary component of the SIS membrane, scientists construct chimeric peptides utilizing the collagen-binding peptide sequence TKTLRT and the pro-angiogenic oligopeptide sequence QSHGPS.…”
Section: Tissue Repair Using Functional Sismentioning
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