Modification of peptide by surface-wave plasma processing

Mechanism of peptide modification by low-temperature microwave plasma

“…The VUV/UV radiation represents the most energetic photons. Even though the intensity of the spectrum in this area seems low, we proved in a previous study 23 molecules. The radiative relaxations detected in the range under 400 nm in the emission spectrum also represents a confirmation of the existence of argon ions in the discharge.…”

“…Thus only radiation with a wavelength higher than 120 nm reach the samples. 23 The spatial position and irradiation time intervals were kept the same in all exposure conditions. The effects of the treatments were investigated by means of physical and chemical properties using X-ray photoelectron spectroscopy (XPS), nuclear magnetic resonance (NMR) spectroscopy, derivatization, and also presence and quantification of the biological function of the biomolecules.…”

Mass spectrometric study of Ar/NH3 surface wave plasma utilized for surface functionalization of ZnO nanoparticles

“…14,15) An important subject of plasma processing that needs to be elucidated is the amination mechanism so that better control of amination can be achieved. In this study, we intend to discuss the effects of the gas mixture ratio of argon to ammonia using high-resolution mass spectrometry and optical emission studies on the surface amination of ZnO NPs.…”

Effects of Nitrogen and Oxygen Radicals on Low-Temperature Bio-Molecule Processing

“…We previously investigated the effect of VUV/UV radiation on biomolecules, and we might assume that the modifications produced only by radiation are negligible. 8) The temperature, monitored by thermolabel, was in all cases lower than 65 C for the direct plasma treatment, and under 50 C when the exposure was done using the grounded grid interposed between plasma and samples. Considering the stability of cystine and that its melting temperature is around 250 C, we can affirm that heating is unimportant in this experiments, which is one of the advantages of using low temperature plasmas.…”

“…8) We were able to induce the loss of biological function through argon microwave plasma exposure of a hormone peptide, arginine vasotocin. The inactivation seems to be only due to a conformation modification resulted from the physical action of the ions produced in the discharge and photophysical effects of the emitted radiation, especially vacuum ultraviolet/ultraviolet (VUV/UV) radiation.…”